STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ureCUrease_alph: urease, alpha subunit. (568 aa)    
Predicted Functional Partners:
ureB
Urease_beta: urease, beta subunit; Belongs to the urease beta subunit family.
 0.999
ureA
Urease_gam: urease, gamma subunit; Belongs to the urease gamma subunit family.
 0.999
ureF
ureF family protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.995
ureD
ureD urease accessory family protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.982
ureE
Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.974
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.968
uca
Urea_carbox: urea carboxylase.
     
 0.909
alc
Allantoicase: allantoicase; Belongs to the allantoicase family.
    
  0.906
alc-2
Allantoicase: allantoicase; Belongs to the allantoicase family.
    
  0.906
allA
Ureidoglycolate hydrolase family protein; Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
    
  0.900
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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