lolA protein (Burkholderia cenocepacia) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

lolA

Outer membrane lipocarrier LolA family protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (229 aa)

Predicted Functional Partners:

lolB

0.927

DM40_2754

0.911

lolD

0.873

DM40_1013

0.843

dsbA

0.785

lptD

0.775

DM40_1627

0.769

DM40_1014

0.757

yaeT

0.744

yfiO

0.731

Your Current Organism:

Burkholderia cenocepacia

NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM40_1013	DM40_1014	DM40_1013	DM40_1014	ftsX-like permease family protein.	ftsX-like permease family protein.	0.953
DM40_1013	lolA	DM40_1013	DM40_1628	ftsX-like permease family protein.	Outer membrane lipocarrier LolA family protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.843
DM40_1013	lolB	DM40_1013	DM40_401	ftsX-like permease family protein.	Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.	0.732
DM40_1013	lolD	DM40_1013	DM40_2753	ftsX-like permease family protein.	Liporeleasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.915
DM40_1014	DM40_1013	DM40_1014	DM40_1013	ftsX-like permease family protein.	ftsX-like permease family protein.	0.953
DM40_1014	lolA	DM40_1014	DM40_1628	ftsX-like permease family protein.	Outer membrane lipocarrier LolA family protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.757
DM40_1014	lolB	DM40_1014	DM40_401	ftsX-like permease family protein.	Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.	0.685
DM40_1014	lolD	DM40_1014	DM40_2753	ftsX-like permease family protein.	Liporeleasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.880
DM40_1627	lolA	DM40_1627	DM40_1628	ftsK/SpoIIIE family protein.	Outer membrane lipocarrier LolA family protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.769
DM40_2754	lolA	DM40_2754	DM40_1628	lolCE: liporeleasing system, transmembrane, LolC/E family protein.	Outer membrane lipocarrier LolA family protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.911
DM40_2754	lolB	DM40_2754	DM40_401	lolCE: liporeleasing system, transmembrane, LolC/E family protein.	Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.	0.732
DM40_2754	lolD	DM40_2754	DM40_2753	lolCE: liporeleasing system, transmembrane, LolC/E family protein.	Liporeleasing system, ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.994
DM40_2754	lptD	DM40_2754	DM40_328	lolCE: liporeleasing system, transmembrane, LolC/E family protein.	Organic solvent tolerance family protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.	0.550
DM40_2754	yaeT	DM40_2754	DM40_2648	lolCE: liporeleasing system, transmembrane, LolC/E family protein.	Outer membrane assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.	0.804
DM40_2754	yfiO	DM40_2754	DM40_2392	lolCE: liporeleasing system, transmembrane, LolC/E family protein.	Outer membrane assembly lipoYfiO family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.	0.638
dsbA	lolA	DM40_521	DM40_1628	Thiol:disulfide interchange protein DsbA.	Outer membrane lipocarrier LolA family protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.785
dsbA	lolB	DM40_521	DM40_401	Thiol:disulfide interchange protein DsbA.	Outer membrane lipoprotein LolB; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.	0.406
dsbA	lptD	DM40_521	DM40_328	Thiol:disulfide interchange protein DsbA.	Organic solvent tolerance family protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.	0.539
dsbA	yfiO	DM40_521	DM40_2392	Thiol:disulfide interchange protein DsbA.	Outer membrane assembly lipoYfiO family protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.	0.419
lolA	DM40_1013	DM40_1628	DM40_1013	Outer membrane lipocarrier LolA family protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	ftsX-like permease family protein.	0.843

page 1 of 3

Server load: low (14%) [HD]

Permalink

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About