STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepNpepN_proteo: aminopeptidase N. (897 aa)    
Predicted Functional Partners:
pepA
Hypothetical protein; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 0.960
gshA-2
Glu_cys_ligase: glutamate--cysteine ligase; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.951
DM40_1201
Peptidase M1 family protein.
  
  
 
0.949
gshA
gshA_ferroox: glutamate--cysteine ligase.
   
 
 0.949
DM40_298
Gamma-glutamyltranspeptidase family protein.
     
 0.947
ggt-2
G_glut_trans: gamma-glutamyltransferase.
     
 0.947
gshB
Glut_syn: glutathione synthase; Belongs to the prokaryotic GSH synthase family.
    
 0.920
glyA2
Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.856
metC
cysta_beta_ly_B: cystathionine beta-lyase.
     
 0.836
ggt
G_glut_trans: gamma-glutamyltransferase.
     
 0.790
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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