Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DM40_1715Type II secretion system (T2SS), K family protein. (114 aa)    
Predicted Functional Partners:
DM40_2751
comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2.
  
  
 0.692
DM40_1282
Type IV leader peptidase family protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
   
  
 0.690
rfaD
ADP-glyceromanno-heptose 6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
       0.613
cysM
cysM: cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
    0.518
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
     
 0.508
lsdA
Levansucrase; Belongs to the glycosyl hydrolase 68 family.
      
 0.507
ssb
Single-stranded DNA-binding family protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
  
 0.491
DM40_1283
Type II secretion system (T2SS), F family protein.
  
  
 0.489
DM40_4023
Type II secretion system (T2SS), F family protein.
  
  
 0.489
gspF
gspF: type II secretion system protein F.
  
  
 0.489
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
Server load: low (24%) [HD]