Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DM40_2047Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family. (627 aa)    
Predicted Functional Partners:
DM40_2045
kduI/IolB family protein.
 
 
 0.999
iolE
Xylose isomerase-like TIM barrel family protein.
 
 
 0.996
DM40_2054
Xylose isomerase-like TIM barrel family protein.
 
 
 0.988
DM40_2048
pfkB carbohydrate kinase family protein.
 
  
 0.975
DM40_2052
Xylose isomerase-like TIM barrel family protein.
 
  
 0.914
iolG
Hypothetical protein; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).
 
  
 0.900
DM40_2056
SIS domain protein.
 
   
 0.772
DM40_2055
Hypothetical protein; Oxidoreductase family, C-terminal alpha/beta domain protein.
 
  
 0.712
DM40_2049
Periplasmic binding s and sugar binding domain of LacI family protein.
 
  
 0.673
fba
Fructose-bisphosphate aldolase, class II, Calvin cycle subtype; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
  
 0.508
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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