STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cobA-2cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (249 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.982
DM40_56
uroporphyrinogen-III synthase HemD family protein.
  
 
 0.927
cobI
Precorrin-2 C20-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
 
 
0.924
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.920
cobA
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 
0.918
cobA-3
cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase.
  
  
 
0.907
DM40_1097
Delta-aminolevulinic acid dehydratase family protein; Belongs to the ALAD family.
 
  
 0.880
DM40_2285
Cobalamin synthesis G family protein.
     
 0.804
cbiA
cobB/CobQ-like glutamine amidotransferase domain protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
   
 0.793
DM40_111
Adenylylsulfate reductase, thioredoxin dependent family protein; Reduction of activated sulfate into sulfite.
 
  
 0.770
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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