STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ghrBGlyoxylate/hydroxypyruvate reductase B; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)    
Predicted Functional Partners:
DM40_4247
Gluconate 2-dehydrogenase subunit 3 family protein.
  
 
 0.936
DM40_2527
Glycerate kinase family protein; Belongs to the glycerate kinase type-1 family.
 
  
 0.923
DM40_558
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein.
 
  
 
0.916
DM40_5802
D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain protein.
 
  
 
0.914
gph
Phosphoglycolate phosphatase, bacterial; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
 
  
 0.912
DM40_1
Aminotransferase class I and II family protein.
  
 
  0.911
DM40_4970
NHL repeat family protein.
   
 
 0.909
glcE
FAD binding domain protein.
   
 0.908
DM40_1426
FAD binding domain protein.
   
 0.908
aceB
malate_syn_A: malate synthase A; Belongs to the malate synthase family.
   
 
 0.908
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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