STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acoCDihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system. (371 aa)    
Predicted Functional Partners:
acoB
Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta.
 
 0.994
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.985
lpdA
lipoamide_DH: dihydrolipoyl dehydrogenase.
 
 0.981
lpdA-3
lipoamide_DH: dihydrolipoyl dehydrogenase.
  
 0.981
lpdA-2
lipoamide_DH: dihydrolipoyl dehydrogenase.
  
 0.980
DM40_170
merR regulatory family protein.
  
 0.977
DM40_3289
cit_synth_II: 2-methylcitrate synthase/citrate synthase II family protein; Belongs to the citrate synthase family.
  
 0.977
gltA
cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 0.977
acoA
Acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha.
 
 0.972
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 0.963
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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