msbA protein (Burkholderia cenocepacia) - STRING interaction network

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msbA

Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (594 aa)

Predicted Functional Partners:

DM40_2961

0.708

DM40_641

0.702

dnaK

0.691

DM40_3431

0.667

DM40_5069

0.645

lpxB

0.642

lpxC

0.630

pgk

0.622

DM40_387

0.620

DM40_2960

0.617

Your Current Organism:

Burkholderia cenocepacia

NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DM40_2960	DM40_2961	DM40_2960	DM40_2961	Hypothetical protein.	O-Antigen ligase family protein.	0.798
DM40_2960	msbA	DM40_2960	DM40_2959	Hypothetical protein.	Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.	0.617
DM40_2961	DM40_2960	DM40_2961	DM40_2960	O-Antigen ligase family protein.	Hypothetical protein.	0.798
DM40_2961	msbA	DM40_2961	DM40_2959	O-Antigen ligase family protein.	Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.	0.708
DM40_3431	DM40_5069	DM40_3431	DM40_5069	Siderophore-interacting FAD-binding domain protein.	type_I_sec_LssB: type I secretion system ATPase family protein.	0.768
DM40_3431	DM40_641	DM40_3431	DM40_641	Siderophore-interacting FAD-binding domain protein.	ABC transporter family protein.	0.768
DM40_3431	msbA	DM40_3431	DM40_2959	Siderophore-interacting FAD-binding domain protein.	Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.	0.667
DM40_387	lpxB	DM40_387	DM40_2643	kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.	lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	0.861
DM40_387	lpxC	DM40_387	DM40_1273	kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	0.859
DM40_387	msbA	DM40_387	DM40_2959	kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.	Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.	0.620
DM40_5069	DM40_3431	DM40_5069	DM40_3431	type_I_sec_LssB: type I secretion system ATPase family protein.	Siderophore-interacting FAD-binding domain protein.	0.768
DM40_5069	msbA	DM40_5069	DM40_2959	type_I_sec_LssB: type I secretion system ATPase family protein.	Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.	0.645
DM40_641	DM40_3431	DM40_641	DM40_3431	ABC transporter family protein.	Siderophore-interacting FAD-binding domain protein.	0.768
DM40_641	dnaK	DM40_641	DM40_1442	ABC transporter family protein.	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.443
DM40_641	msbA	DM40_641	DM40_2959	ABC transporter family protein.	Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.	0.702
dnaK	DM40_641	DM40_1442	DM40_641	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	ABC transporter family protein.	0.443
dnaK	msbA	DM40_1442	DM40_2959	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Lipid A export permease/ATP-binding protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.	0.691
dnaK	pgk	DM40_1442	DM40_259	Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Phosphoglycerate kinase family protein; Belongs to the phosphoglycerate kinase family.	0.576
lpxB	DM40_387	DM40_2643	DM40_387	lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.	0.861
lpxB	lpxC	DM40_2643	DM40_1273	lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.	0.895

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