| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DM40_2505 | nadE | DM40_2505 | DM40_3126 | Isochorismatase family protein. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.690 |
| DM40_2505 | pncB | DM40_2505 | DM40_1763 | Isochorismatase family protein. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.976 |
| DM40_4847 | nadD | DM40_4847 | DM40_2949 | Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family. | Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.940 |
| DM40_4847 | nadE | DM40_4847 | DM40_3126 | Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.947 |
| DM40_4847 | nadE-2 | DM40_4847 | DM40_48 | Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.967 |
| DM40_4847 | pncB | DM40_4847 | DM40_1763 | Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family. | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.954 |
| DM40_4847 | pntA | DM40_4847 | DM40_5302 | Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family. | pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit. | 0.900 |
| DM40_4847 | pntB | DM40_4847 | DM40_5303 | Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family. | NAD(P) transhydrogenase subunit beta. | 0.900 |
| DM40_4847 | ppnK | DM40_4847 | DM40_1436 | Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family. | ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.932 |
| cutC | nadE | DM40_537 | DM40_3126 | cutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.702 |
| cutC | nadE-2 | DM40_537 | DM40_48 | cutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.705 |
| nadD | DM40_4847 | DM40_2949 | DM40_4847 | Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Bifunctional NMN adenylyltransferase/Nudix hydrolase; Belongs to the Nudix hydrolase family. | 0.940 |
| nadD | nadE | DM40_2949 | DM40_3126 | Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.942 |
| nadD | nadE-2 | DM40_2949 | DM40_48 | Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.958 |
| nadD | pncB | DM40_2949 | DM40_1763 | Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. | 0.941 |
| nadD | pntA | DM40_2949 | DM40_5302 | Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit. | 0.906 |
| nadD | pntB | DM40_2949 | DM40_5303 | Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD(P) transhydrogenase subunit beta. | 0.904 |
| nadD | ppnK | DM40_2949 | DM40_1436 | Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | ATP-NAD kinase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.949 |
| nadD | ribD | DM40_2949 | DM40_1612 | Cytidylyltransferase family protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.773 |
| nadE | DM40_2505 | DM40_3126 | DM40_2505 | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | Isochorismatase family protein. | 0.690 |