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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
phnYphnAcAld_DH: putative phosphonoacetaldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (484 aa)    
Predicted Functional Partners:
phnA
hydr_PhnA: phosphonoacetate hydrolase.
 
  
 0.992
phnW
2-aminoethylphosphonate--pyruvate transaminase; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
 
 0.967
phnW-2
2-aminoethylphosphonate aminotransferase family protein; Involved in phosphonate degradation; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
  
 0.950
aepY
ppyr-DeCO2ase: phosphonopyruvate decarboxylase.
  
 0.922
DM40_3144
Putative HD phosphohydrolase.
       0.781
phnV
phnV: 2-aminoethylphosphonate ABC transport system, membrane component PhnV.
       0.781
phnU
phnU: 2-aminoethylphosphonate ABC transporter, permease protein.
       0.781
phnT
phnT: 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Belongs to the ABC transporter superfamily.
       0.781
phnS
phnS: 2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein.
     
 0.695
DM40_1
Aminotransferase class I and II family protein.
  
     0.601
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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