STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DM40_3550Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family. (573 aa)    
Predicted Functional Partners:
ilvN
Acolac_sm: acetolactate synthase, small subunit.
 
 0.986
DM40_1030
Malic enzyme, NAD binding domain protein; Belongs to the malic enzymes family.
  
 0.939
DM40_1335
Malic enzyme, NAD binding domain protein.
  
 0.939
DM40_4997
Malic enzyme, NAD binding domain protein.
  
 0.939
DM40_5120
Thiamine pyrophosphate enzyme, central domain protein; Belongs to the TPP enzyme family.
  
  
 
0.917
pyk
Pyruv_kin: pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.912
ackA
ackA: acetate kinase.
    
 0.910
DM40_1427
FAD binding domain protein.
    
 0.907
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.907
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
 
 
 0.906
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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