Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DM40_3652Hypothetical protein; Glutathione S-transferase, N-terminal domain protein; Belongs to the GST superfamily. (205 aa)    
Predicted Functional Partners:
gor
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
  
 
 0.940
DM40_1272
ahpC/TSA family protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
  
 
  0.935
gshB
Glut_syn: glutathione synthase; Belongs to the prokaryotic GSH synthase family.
 
  
 0.934
DM40_2671
Glutathione peroxidase family protein; Belongs to the glutathione peroxidase family.
   
 
 0.919
DM40_313
chaC-like family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
  
  
  0.912
grxD
Monothiol glutaredoxin, Grx4 family; Belongs to the glutaredoxin family. Monothiol subfamily.
 
  
 0.707
ggt
G_glut_trans: gamma-glutamyltransferase.
  
  
 0.700
gloA
glyox_I: lactoylglutathione lyase.
  
    0.692
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
   0.690
lysS
lysS_bact: lysine--tRNA ligase; Belongs to the class-II aminoacyl-tRNA synthetase family.
   
  0.669
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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