Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DM40_386trkA-N domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (668 aa)    
Predicted Functional Partners:
DM40_3776
NADPH-dependent FMN reductase family protein.
  
 
 0.901
flgF
flgF: flagellar basal-body rod protein FlgF; Belongs to the flagella basal body rod proteins family.
    
   0.776
DM40_387
kpsF: sugar isomerase, KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.
    
 0.739
DM40_4250
Ketopantoate reductase PanE/ApbA family protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
 
  
0.713
lptA
Lipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
 
     0.681
lptC
Lipopolysaccharide-assembly, LptC-related family protein.
       0.654
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
       0.621
DM40_388
Phosphatase, YrbI family.
       0.616
lptB
ABC transporter family protein.
       0.616
DM40_3278
ATPase-IB1_Cu: copper-translocating P-type ATPase.
  
  
 0.557
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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