Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
chbChitobiase. (827 aa)    
Predicted Functional Partners:
nagE
PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component.
 
  
 0.992
ptsP
PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
  
  
 0.933
nagZ
Hypothetical protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
    
 0.921
hutH
hutH: histidine ammonia-lyase.
   
    0.730
DM40_5313
Aromatic amino acid lyase family protein.
   
    0.730
DM40_4235
Putative beta-mannosidase.
 
 
 0.561
anmK
Hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
    
  0.550
cutC
cutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family.
 
     0.516
DM40_198
N-acetylmuramoyl-L-alanine amidase family protein.
     
 0.502
DM40_1300
N-acetylmuramoyl-L-alanine amidase family protein.
     
  0.500
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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