STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ptsHPTS_HPr_: phosphocarrier, HPr family protein. (89 aa)    
Predicted Functional Partners:
ptsP
PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
 
 0.999
ptsP-2
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
DM40_464
PTS system fructose IIA component family protein.
 
 
 0.993
nagE
PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component.
 
 
 0.966
hprK
HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
 
 
 0.935
DM40_5095
PTS HPr component phosphorylation site family protein.
     
 0.905
DM40_394
Band 3 cytoplasmic domain protein.
 
  
 0.881
DM40_5778
Helix-turn-helix domain protein.
   
 
 0.637
DM40_3373
Periplasmic binding s and sugar binding domain of LacI family protein.
 
 
 
 0.581
DM40_1896
Periplasmic binding s and sugar binding domain of LacI family protein.
 
 
 
 0.575
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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