Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DM40_4992Hypothetical protein. (162 aa)    
Predicted Functional Partners:
lcdH
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain protein; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.
   
 0.994
DM40_4994
Hypothetical protein.
 
  
 0.923
DM40_1918
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain protein.
   
 0.876
DM40_4990
Gamma-butyrobetaine dioxygenase.
 
     0.755
DM40_4991
Alpha/beta hydrolase fold family protein.
     
 0.665
choX-2
ABC_choline_bnd: choline ABC transporter, periplasmic binding family protein.
 
   
 0.499
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.
   
   0.479
DM40_5011
Helix-turn-helix domain protein.
  
     0.474
fliG
fliG: flagellar motor switch protein FliG.
    
   0.464
fliA
RNA polymerase sigma factor, FliA/WhiG family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
    
   0.464
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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