Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dmpG4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase. (339 aa)    
Predicted Functional Partners:
DM40_5001
ac_ald_DH_ac: acetaldehyde dehydrogenase.
 
 0.999
mhpD
2-keto-4-pentenoate hydratase.
 
 
 0.995
mhpC
2-hydroxy-6-oxononadienedioate/2-hydroxy-6- oxononatrienedioate hydrolase.
 
 
 0.923
mhpB
2,3-dihydroxyphenylpropionate/2, 3-dihydroxicinnamic acid 1,2-dioxygenase.
 
  
 0.894
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.826
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
  
 0.822
hpaH
hpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase.
 
  
 0.795
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
  
 0.769
mhpA
3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase.
 
   0.760
DM40_1444
Aminotransferase class IV family protein.
  
 
 0.700
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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