Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DM40_5288sigma70-ECF: RNA polymerase sigma factor, sigma-70 family protein. (182 aa)    
Predicted Functional Partners:
DM40_1790
Hypothetical protein; Anti sigma-E RseA, N-terminal domain protein.
  
 
 0.791
DM40_5362
sigma70-ECF: RNA polymerase sigma factor, sigma-70 family protein.
  
   
 0.749
DM40_4503
sigma70-ECF: RNA polymerase sigma factor, sigma-70 family protein.
  
   
 0.748
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.668
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.665
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.653
DM40_5279
Putative transmembrane anti-sigma factor.
 
 
 0.618
DM40_791
Putative transmembrane regulator PrtR.
  
 
 0.581
DM40_5378
cheR methyltransferase, all-alpha domain protein.
   
 
 0.569
DM40_1517
Hypothetical protein; Anti sigma-E RseA, N-terminal domain protein.
  
 
 0.550
Your Current Organism:
Burkholderia cenocepacia
NCBI taxonomy Id: 95486
Other names: ATCC BAA-245, ATCC:BAA:245, B. cenocepacia, Burkholderia cenocepacia Vandamme et al. 2003, Burkholderia cepacia genomovar III, Burkholderia cepacia genomovar IIIb, CCM 4899, CCUG 48434, DSM 16553, LMG 16656, LMG:16656, NCTC 13227
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