node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATF3 | ATF4 | ENSPANP00000011720 | ENSPANP00000013369 | Activating transcription factor 3. | Activating transcription factor 4. | 0.785 |
ATF3 | ATF5 | ENSPANP00000011720 | ENSPANP00000008592 | Activating transcription factor 3. | Activating transcription factor 5. | 0.425 |
ATF3 | CEBPB | ENSPANP00000011720 | ENSPANP00000014611 | Activating transcription factor 3. | CCAAT/enhancer-binding protein. | 0.739 |
ATF3 | CEBPG | ENSPANP00000011720 | ENSPANP00000001360 | Activating transcription factor 3. | CCAAT enhancer binding protein gamma. | 0.616 |
ATF3 | DDIT3 | ENSPANP00000011720 | ENSPANP00000018338 | Activating transcription factor 3. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.910 |
ATF3 | ENSPANP00000021624 | ENSPANP00000011720 | ENSPANP00000021624 | Activating transcription factor 3. | BZIP domain-containing protein. | 0.766 |
ATF4 | ATF3 | ENSPANP00000013369 | ENSPANP00000011720 | Activating transcription factor 4. | Activating transcription factor 3. | 0.785 |
ATF4 | CEBPB | ENSPANP00000013369 | ENSPANP00000014611 | Activating transcription factor 4. | CCAAT/enhancer-binding protein. | 0.924 |
ATF4 | CEBPG | ENSPANP00000013369 | ENSPANP00000001360 | Activating transcription factor 4. | CCAAT enhancer binding protein gamma. | 0.916 |
ATF4 | DDIT3 | ENSPANP00000013369 | ENSPANP00000018338 | Activating transcription factor 4. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.979 |
ATF5 | ATF3 | ENSPANP00000008592 | ENSPANP00000011720 | Activating transcription factor 5. | Activating transcription factor 3. | 0.425 |
ATF5 | CEBPB | ENSPANP00000008592 | ENSPANP00000014611 | Activating transcription factor 5. | CCAAT/enhancer-binding protein. | 0.450 |
ATF5 | CEBPG | ENSPANP00000008592 | ENSPANP00000001360 | Activating transcription factor 5. | CCAAT enhancer binding protein gamma. | 0.727 |
ATF5 | DDIT3 | ENSPANP00000008592 | ENSPANP00000018338 | Activating transcription factor 5. | DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] | 0.525 |
CEBPB | ATF3 | ENSPANP00000014611 | ENSPANP00000011720 | CCAAT/enhancer-binding protein. | Activating transcription factor 3. | 0.739 |
CEBPB | ATF4 | ENSPANP00000014611 | ENSPANP00000013369 | CCAAT/enhancer-binding protein. | Activating transcription factor 4. | 0.924 |
CEBPB | ATF5 | ENSPANP00000014611 | ENSPANP00000008592 | CCAAT/enhancer-binding protein. | Activating transcription factor 5. | 0.450 |
CEBPB | CEBPG | ENSPANP00000014611 | ENSPANP00000001360 | CCAAT/enhancer-binding protein. | CCAAT enhancer binding protein gamma. | 0.910 |
CEBPB | COX5A | ENSPANP00000014611 | ENSPANP00000043483 | CCAAT/enhancer-binding protein. | Uncharacterized protein. | 0.594 |
CEBPB | COX5A-2 | ENSPANP00000014611 | ENSPANP00000034446 | CCAAT/enhancer-binding protein. | Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] | 0.594 |