| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPANP00000007352 | IL1A | ENSPANP00000007352 | ENSPANP00000042455 | Uncharacterized protein. | Interleukin-1; Belongs to the IL-1 family. | 0.973 |
| ENSPANP00000007352 | IL1B | ENSPANP00000007352 | ENSPANP00000011447 | Uncharacterized protein. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.994 |
| ENSPANP00000007352 | IL1RL1 | ENSPANP00000007352 | ENSPANP00000002036 | Uncharacterized protein. | Interleukin 1 receptor like 1. | 0.984 |
| ENSPANP00000007352 | IL1RN | ENSPANP00000007352 | ENSPANP00000039891 | Uncharacterized protein. | Interleukin-1. | 0.922 |
| ENSPANP00000007352 | IL33 | ENSPANP00000007352 | ENSPANP00000019226 | Uncharacterized protein. | Interleukin 33. | 0.994 |
| ENSPANP00000007352 | IRAK1 | ENSPANP00000007352 | ENSPANP00000000920 | Uncharacterized protein. | Interleukin 1 receptor associated kinase 1. | 0.903 |
| ENSPANP00000007352 | IRAK2 | ENSPANP00000007352 | ENSPANP00000008073 | Uncharacterized protein. | Interleukin 1 receptor associated kinase 2. | 0.866 |
| ENSPANP00000007352 | IRAK4 | ENSPANP00000007352 | ENSPANP00000008181 | Uncharacterized protein. | Interleukin 1 receptor associated kinase 4. | 0.621 |
| ENSPANP00000007352 | MYD88 | ENSPANP00000007352 | ENSPANP00000015354 | Uncharacterized protein. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.970 |
| ENSPANP00000007352 | TRAF6 | ENSPANP00000007352 | ENSPANP00000004422 | Uncharacterized protein. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.663 |
| IL1A | ENSPANP00000007352 | ENSPANP00000042455 | ENSPANP00000007352 | Interleukin-1; Belongs to the IL-1 family. | Uncharacterized protein. | 0.973 |
| IL1A | IL1B | ENSPANP00000042455 | ENSPANP00000011447 | Interleukin-1; Belongs to the IL-1 family. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.999 |
| IL1A | IL1RL1 | ENSPANP00000042455 | ENSPANP00000002036 | Interleukin-1; Belongs to the IL-1 family. | Interleukin 1 receptor like 1. | 0.760 |
| IL1A | IL1RN | ENSPANP00000042455 | ENSPANP00000039891 | Interleukin-1; Belongs to the IL-1 family. | Interleukin-1. | 0.706 |
| IL1A | IL33 | ENSPANP00000042455 | ENSPANP00000019226 | Interleukin-1; Belongs to the IL-1 family. | Interleukin 33. | 0.705 |
| IL1A | IRAK1 | ENSPANP00000042455 | ENSPANP00000000920 | Interleukin-1; Belongs to the IL-1 family. | Interleukin 1 receptor associated kinase 1. | 0.759 |
| IL1A | IRAK2 | ENSPANP00000042455 | ENSPANP00000008073 | Interleukin-1; Belongs to the IL-1 family. | Interleukin 1 receptor associated kinase 2. | 0.615 |
| IL1A | IRAK4 | ENSPANP00000042455 | ENSPANP00000008181 | Interleukin-1; Belongs to the IL-1 family. | Interleukin 1 receptor associated kinase 4. | 0.690 |
| IL1A | MYD88 | ENSPANP00000042455 | ENSPANP00000015354 | Interleukin-1; Belongs to the IL-1 family. | Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. | 0.770 |
| IL1A | TRAF6 | ENSPANP00000042455 | ENSPANP00000004422 | Interleukin-1; Belongs to the IL-1 family. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.750 |
