| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATR | ATRIP | ENSPANP00000011874 | ENSPANP00000010627 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | ATR interacting protein. | 0.999 |
| ATR | CDC25A | ENSPANP00000011874 | ENSPANP00000011384 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Cell division cycle 25A. | 0.825 |
| ATR | CDC25C | ENSPANP00000011874 | ENSPANP00000014979 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Cell division cycle 25C. | 0.804 |
| ATR | CDC45 | ENSPANP00000011874 | ENSPANP00000035423 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Cell division cycle 45. | 0.870 |
| ATR | CHEK1 | ENSPANP00000011874 | ENSPANP00000002718 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Checkpoint kinase 1. | 0.991 |
| ATR | CLSPN | ENSPANP00000011874 | ENSPANP00000017837 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Claspin. | 0.939 |
| ATR | MCM4 | ENSPANP00000011874 | ENSPANP00000010964 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA helicase; Belongs to the MCM family. | 0.884 |
| ATR | RAD51 | ENSPANP00000011874 | ENSPANP00000030557 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.936 |
| ATR | TOPBP1 | ENSPANP00000011874 | ENSPANP00000006180 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | DNA topoisomerase II binding protein 1. | 0.980 |
| ATR | TP53 | ENSPANP00000011874 | ENSPANP00000033477 | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.995 |
| ATRIP | ATR | ENSPANP00000010627 | ENSPANP00000011874 | ATR interacting protein. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.999 |
| ATRIP | CDC25A | ENSPANP00000010627 | ENSPANP00000011384 | ATR interacting protein. | Cell division cycle 25A. | 0.537 |
| ATRIP | CDC25C | ENSPANP00000010627 | ENSPANP00000014979 | ATR interacting protein. | Cell division cycle 25C. | 0.488 |
| ATRIP | CDC45 | ENSPANP00000010627 | ENSPANP00000035423 | ATR interacting protein. | Cell division cycle 45. | 0.682 |
| ATRIP | CHEK1 | ENSPANP00000010627 | ENSPANP00000002718 | ATR interacting protein. | Checkpoint kinase 1. | 0.965 |
| ATRIP | CLSPN | ENSPANP00000010627 | ENSPANP00000017837 | ATR interacting protein. | Claspin. | 0.823 |
| ATRIP | MCM4 | ENSPANP00000010627 | ENSPANP00000010964 | ATR interacting protein. | DNA helicase; Belongs to the MCM family. | 0.544 |
| ATRIP | RAD51 | ENSPANP00000010627 | ENSPANP00000030557 | ATR interacting protein. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.749 |
| ATRIP | TOPBP1 | ENSPANP00000010627 | ENSPANP00000006180 | ATR interacting protein. | DNA topoisomerase II binding protein 1. | 0.978 |
| ATRIP | TP53 | ENSPANP00000010627 | ENSPANP00000033477 | ATR interacting protein. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.585 |
