| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BHMT | DMGDH | ENSPANP00000000909 | ENSPANP00000003809 | Betaine--homocysteine S-methyltransferase. | Dimethylglycine dehydrogenase. | 0.986 |
| BHMT | GLDC | ENSPANP00000000909 | ENSPANP00000047498 | Betaine--homocysteine S-methyltransferase. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.811 |
| BHMT | MTHFD2 | ENSPANP00000000909 | ENSPANP00000011728 | Betaine--homocysteine S-methyltransferase. | Uncharacterized protein. | 0.698 |
| BHMT | MTHFD2L | ENSPANP00000000909 | ENSPANP00000003052 | Betaine--homocysteine S-methyltransferase. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | 0.651 |
| BHMT | MTHFR | ENSPANP00000000909 | ENSPANP00000008861 | Betaine--homocysteine S-methyltransferase. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.964 |
| BHMT | MTR | ENSPANP00000000909 | ENSPANP00000017831 | Betaine--homocysteine S-methyltransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.957 |
| BHMT | PIPOX | ENSPANP00000000909 | ENSPANP00000019886 | Betaine--homocysteine S-methyltransferase. | Pipecolic acid and sarcosine oxidase. | 0.726 |
| BHMT | SHMT1 | ENSPANP00000000909 | ENSPANP00000019762 | Betaine--homocysteine S-methyltransferase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.717 |
| BHMT | SHMT2 | ENSPANP00000000909 | ENSPANP00000001359 | Betaine--homocysteine S-methyltransferase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.681 |
| DMGDH | BHMT | ENSPANP00000003809 | ENSPANP00000000909 | Dimethylglycine dehydrogenase. | Betaine--homocysteine S-methyltransferase. | 0.986 |
| DMGDH | GART | ENSPANP00000003809 | ENSPANP00000011141 | Dimethylglycine dehydrogenase. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.958 |
| DMGDH | GLDC | ENSPANP00000003809 | ENSPANP00000047498 | Dimethylglycine dehydrogenase. | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. | 0.963 |
| DMGDH | MTHFD2 | ENSPANP00000003809 | ENSPANP00000011728 | Dimethylglycine dehydrogenase. | Uncharacterized protein. | 0.970 |
| DMGDH | MTHFD2L | ENSPANP00000003809 | ENSPANP00000003052 | Dimethylglycine dehydrogenase. | Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like. | 0.978 |
| DMGDH | MTHFR | ENSPANP00000003809 | ENSPANP00000008861 | Dimethylglycine dehydrogenase. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.982 |
| DMGDH | MTR | ENSPANP00000003809 | ENSPANP00000017831 | Dimethylglycine dehydrogenase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.977 |
| DMGDH | PIPOX | ENSPANP00000003809 | ENSPANP00000019886 | Dimethylglycine dehydrogenase. | Pipecolic acid and sarcosine oxidase. | 0.962 |
| DMGDH | SHMT1 | ENSPANP00000003809 | ENSPANP00000019762 | Dimethylglycine dehydrogenase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.982 |
| DMGDH | SHMT2 | ENSPANP00000003809 | ENSPANP00000001359 | Dimethylglycine dehydrogenase. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.985 |
| GART | DMGDH | ENSPANP00000011141 | ENSPANP00000003809 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Dimethylglycine dehydrogenase. | 0.958 |
