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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CD4CD4 molecule. (458 aa)    
Predicted Functional Partners:
CD8B
Ig-like domain-containing protein.
   
 
 0.997
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.996
CD8A
CD8a molecule.
   
 0.996
ZAP70
Tyrosine-protein kinase.
   
 0.996
HLA-DRA
Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family.
   
 0.995
HLA-DOB
Major histocompatibility complex, class II, DO beta.
   
 0.994
HLA-DOA
Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.
   
 0.994
IL16
Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
    
 0.993
LOC101016766
Ig-like domain-containing protein.
    
  0.992
HLA-DPA1
Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family.
   
 
  0.992
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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