Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CD4CD4 molecule. (458 aa)    
Predicted Functional Partners:
LCK
Tyrosine-protein kinase.
   
 0.986
ZAP70
Tyrosine-protein kinase.
    
 0.984
CD8B
Ig-like domain-containing protein.
     
 0.978
IL16
Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
    
 0.975
CD8A
CD8a molecule.
   
 
 0.973
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.958
HLA-DOA
Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family.
   
 0.937
LOC101001669
Ig-like domain-containing protein.
   
 0.932
LOC101000981
Ig-like domain-containing protein.
   
 0.930
HLA-DOB
Major histocompatibility complex, class II, DO beta.
   
 0.930
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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