| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BLM | ENSPANP00000030504 | ENSPANP00000014473 | ENSPANP00000030504 | BLM RecQ like helicase. | RPA_C domain-containing protein. | 0.855 |
| BLM | POLD1 | ENSPANP00000014473 | ENSPANP00000008432 | BLM RecQ like helicase. | DNA polymerase. | 0.726 |
| BLM | RMI2 | ENSPANP00000014473 | ENSPANP00000027952 | BLM RecQ like helicase. | RecQ mediated genome instability 2. | 0.999 |
| BLM | RPA1 | ENSPANP00000014473 | ENSPANP00000019489 | BLM RecQ like helicase. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.995 |
| BLM | RPA2 | ENSPANP00000014473 | ENSPANP00000027721 | BLM RecQ like helicase. | Replication protein A2. | 0.989 |
| BLM | RPA3 | ENSPANP00000014473 | ENSPANP00000005086 | BLM RecQ like helicase. | Uncharacterized protein. | 0.988 |
| BLM | TOP3A | ENSPANP00000014473 | ENSPANP00000019759 | BLM RecQ like helicase. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.999 |
| BLM | TOP3B | ENSPANP00000014473 | ENSPANP00000015927 | BLM RecQ like helicase. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.934 |
| BLM | WRN | ENSPANP00000014473 | ENSPANP00000018132 | BLM RecQ like helicase. | WRN RecQ like helicase. | 0.607 |
| ENSPANP00000030504 | BLM | ENSPANP00000030504 | ENSPANP00000014473 | RPA_C domain-containing protein. | BLM RecQ like helicase. | 0.855 |
| ENSPANP00000030504 | POLD1 | ENSPANP00000030504 | ENSPANP00000008432 | RPA_C domain-containing protein. | DNA polymerase. | 0.861 |
| ENSPANP00000030504 | RMI2 | ENSPANP00000030504 | ENSPANP00000027952 | RPA_C domain-containing protein. | RecQ mediated genome instability 2. | 0.471 |
| ENSPANP00000030504 | RPA1 | ENSPANP00000030504 | ENSPANP00000019489 | RPA_C domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.961 |
| ENSPANP00000030504 | RPA3 | ENSPANP00000030504 | ENSPANP00000005086 | RPA_C domain-containing protein. | Uncharacterized protein. | 0.903 |
| ENSPANP00000030504 | TOP3A | ENSPANP00000030504 | ENSPANP00000019759 | RPA_C domain-containing protein. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.872 |
| ENSPANP00000030504 | WRN | ENSPANP00000030504 | ENSPANP00000018132 | RPA_C domain-containing protein. | WRN RecQ like helicase. | 0.885 |
| ENSPANP00000030504 | XPA | ENSPANP00000030504 | ENSPANP00000019060 | RPA_C domain-containing protein. | XPA, DNA damage recognition and repair factor. | 0.892 |
| POLD1 | BLM | ENSPANP00000008432 | ENSPANP00000014473 | DNA polymerase. | BLM RecQ like helicase. | 0.726 |
| POLD1 | ENSPANP00000030504 | ENSPANP00000008432 | ENSPANP00000030504 | DNA polymerase. | RPA_C domain-containing protein. | 0.861 |
| POLD1 | RMI2 | ENSPANP00000008432 | ENSPANP00000027952 | DNA polymerase. | RecQ mediated genome instability 2. | 0.435 |
