| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CREBBP | EP300 | ENSPANP00000013793 | ENSPANP00000013403 | CREB binding protein. | E1A binding protein p300. | 0.999 |
| CREBBP | MED1 | ENSPANP00000013793 | ENSPANP00000020534 | CREB binding protein. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.771 |
| CREBBP | NCOR1 | ENSPANP00000013793 | ENSPANP00000019731 | CREB binding protein. | Nuclear receptor corepressor 1. | 0.821 |
| CREBBP | NCOR2 | ENSPANP00000013793 | ENSPANP00000029106 | CREB binding protein. | Nuclear receptor corepressor 2. | 0.773 |
| CREBBP | PPARG | ENSPANP00000013793 | ENSPANP00000043034 | CREB binding protein. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.960 |
| CREBBP | PPARGC1A | ENSPANP00000013793 | ENSPANP00000018518 | CREB binding protein. | PPARG coactivator 1 alpha. | 0.779 |
| CREBBP | RXRA | ENSPANP00000013793 | ENSPANP00000032125 | CREB binding protein. | Retinoid X receptor alpha. | 0.925 |
| CREBBP | RXRB | ENSPANP00000013793 | ENSPANP00000012407 | CREB binding protein. | Retinoid X receptor beta. | 0.857 |
| CREBBP | RXRG | ENSPANP00000013793 | ENSPANP00000004047 | CREB binding protein. | Retinoid X receptor gamma. | 0.890 |
| CREBBP | SIRT1 | ENSPANP00000013793 | ENSPANP00000020463 | CREB binding protein. | Sirtuin 1. | 0.820 |
| EP300 | CREBBP | ENSPANP00000013403 | ENSPANP00000013793 | E1A binding protein p300. | CREB binding protein. | 0.999 |
| EP300 | MED1 | ENSPANP00000013403 | ENSPANP00000020534 | E1A binding protein p300. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.932 |
| EP300 | NCOR1 | ENSPANP00000013403 | ENSPANP00000019731 | E1A binding protein p300. | Nuclear receptor corepressor 1. | 0.906 |
| EP300 | NCOR2 | ENSPANP00000013403 | ENSPANP00000029106 | E1A binding protein p300. | Nuclear receptor corepressor 2. | 0.693 |
| EP300 | PPARG | ENSPANP00000013403 | ENSPANP00000043034 | E1A binding protein p300. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.961 |
| EP300 | PPARGC1A | ENSPANP00000013403 | ENSPANP00000018518 | E1A binding protein p300. | PPARG coactivator 1 alpha. | 0.812 |
| EP300 | RXRA | ENSPANP00000013403 | ENSPANP00000032125 | E1A binding protein p300. | Retinoid X receptor alpha. | 0.858 |
| EP300 | RXRB | ENSPANP00000013403 | ENSPANP00000012407 | E1A binding protein p300. | Retinoid X receptor beta. | 0.838 |
| EP300 | RXRG | ENSPANP00000013403 | ENSPANP00000004047 | E1A binding protein p300. | Retinoid X receptor gamma. | 0.835 |
| EP300 | SIRT1 | ENSPANP00000013403 | ENSPANP00000020463 | E1A binding protein p300. | Sirtuin 1. | 0.913 |
