node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C12orf4 | EXOC8 | ENSPANP00000007510 | ENSPANP00000008664 | Chromosome 12 open reading frame 4. | Exocyst complex component 8. | 0.770 |
C12orf4 | MTERF1 | ENSPANP00000007510 | ENSPANP00000018616 | Chromosome 12 open reading frame 4. | Mitochondrial transcription termination factor 1. | 0.431 |
C12orf4 | PELO | ENSPANP00000007510 | ENSPANP00000003679 | Chromosome 12 open reading frame 4. | Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. | 0.420 |
C12orf4 | PPP1R21 | ENSPANP00000007510 | ENSPANP00000002635 | Chromosome 12 open reading frame 4. | Protein phosphatase 1 regulatory subunit 21. | 0.647 |
C12orf4 | SLX1A | ENSPANP00000007510 | ENSPANP00000012513 | Chromosome 12 open reading frame 4. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.771 |
C12orf4 | TBCK | ENSPANP00000007510 | ENSPANP00000002531 | Chromosome 12 open reading frame 4. | TBC1 domain containing kinase. | 0.614 |
C12orf4 | TMEM106C | ENSPANP00000007510 | ENSPANP00000005382 | Chromosome 12 open reading frame 4. | Transmembrane protein 106C. | 0.479 |
C12orf4 | TMEM184C | ENSPANP00000007510 | ENSPANP00000002707 | Chromosome 12 open reading frame 4. | Transmembrane protein 184C. | 0.434 |
C12orf4 | ZNF330 | ENSPANP00000007510 | ENSPANP00000003475 | Chromosome 12 open reading frame 4. | Zinc finger protein 330. | 0.480 |
EXOC8 | C12orf4 | ENSPANP00000008664 | ENSPANP00000007510 | Exocyst complex component 8. | Chromosome 12 open reading frame 4. | 0.770 |
EXOC8 | SLX1A | ENSPANP00000008664 | ENSPANP00000012513 | Exocyst complex component 8. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.718 |
MTERF1 | C12orf4 | ENSPANP00000018616 | ENSPANP00000007510 | Mitochondrial transcription termination factor 1. | Chromosome 12 open reading frame 4. | 0.431 |
PELO | C12orf4 | ENSPANP00000003679 | ENSPANP00000007510 | Protein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. | Chromosome 12 open reading frame 4. | 0.420 |
PPP1R21 | C12orf4 | ENSPANP00000002635 | ENSPANP00000007510 | Protein phosphatase 1 regulatory subunit 21. | Chromosome 12 open reading frame 4. | 0.647 |
PPP1R21 | TBCK | ENSPANP00000002635 | ENSPANP00000002531 | Protein phosphatase 1 regulatory subunit 21. | TBC1 domain containing kinase. | 0.496 |
PPP1R21 | ZNF330 | ENSPANP00000002635 | ENSPANP00000003475 | Protein phosphatase 1 regulatory subunit 21. | Zinc finger protein 330. | 0.479 |
SLX1A | C12orf4 | ENSPANP00000012513 | ENSPANP00000007510 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | Chromosome 12 open reading frame 4. | 0.771 |
SLX1A | EXOC8 | ENSPANP00000012513 | ENSPANP00000008664 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | Exocyst complex component 8. | 0.718 |
TBCK | C12orf4 | ENSPANP00000002531 | ENSPANP00000007510 | TBC1 domain containing kinase. | Chromosome 12 open reading frame 4. | 0.614 |
TBCK | PPP1R21 | ENSPANP00000002531 | ENSPANP00000002635 | TBC1 domain containing kinase. | Protein phosphatase 1 regulatory subunit 21. | 0.496 |