STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHX57DExH-box helicase 57. (1387 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
  0.984
ITSN1
Uncharacterized protein.
   
  0.828
AP2M1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
    
 0.827
AP2S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.770
STXBP4
Syntaxin binding protein 4.
   
 0.738
MLST8
MTOR associated protein, LST8 homolog.
      
 0.697
UTP18
UTP18 small subunit processome component.
   
 0.696
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1.
    
 0.673
PDCD11
Programmed cell death 11.
  
 0.672
SLU7
SLU7 homolog, splicing factor.
    
 0.661
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.