| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BRCA1 | MDC1 | ENSPANP00000027226 | ENSPANP00000013959 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Mediator of DNA damage checkpoint 1. | 0.973 |
| BRCA1 | NFIC | ENSPANP00000027226 | ENSPANP00000031968 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.690 |
| GATA4 | GATA6 | ENSPANP00000006452 | ENSPANP00000003815 | GATA binding protein 4. | GATA binding protein 6. | 0.738 |
| GATA4 | NFIA | ENSPANP00000006452 | ENSPANP00000031305 | GATA binding protein 4. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.680 |
| GATA4 | NFIB | ENSPANP00000006452 | ENSPANP00000030927 | GATA binding protein 4. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.733 |
| GATA4 | NFIC | ENSPANP00000006452 | ENSPANP00000031968 | GATA binding protein 4. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.733 |
| GATA4 | NFIX | ENSPANP00000006452 | ENSPANP00000040828 | GATA binding protein 4. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.718 |
| GATA6 | GATA4 | ENSPANP00000003815 | ENSPANP00000006452 | GATA binding protein 6. | GATA binding protein 4. | 0.738 |
| GATA6 | NFIA | ENSPANP00000003815 | ENSPANP00000031305 | GATA binding protein 6. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.666 |
| GATA6 | NFIB | ENSPANP00000003815 | ENSPANP00000030927 | GATA binding protein 6. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.617 |
| GATA6 | NFIC | ENSPANP00000003815 | ENSPANP00000031968 | GATA binding protein 6. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.726 |
| GATA6 | NFIX | ENSPANP00000003815 | ENSPANP00000040828 | GATA binding protein 6. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.651 |
| KLF12 | NFIC | ENSPANP00000005881 | ENSPANP00000031968 | Kruppel like factor 12. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.752 |
| KLF12 | TFAP2A | ENSPANP00000005881 | ENSPANP00000013611 | Kruppel like factor 12. | Transcription factor AP-2 alpha. | 0.677 |
| MDC1 | BRCA1 | ENSPANP00000013959 | ENSPANP00000027226 | Mediator of DNA damage checkpoint 1. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.973 |
| MDC1 | NFIC | ENSPANP00000013959 | ENSPANP00000031968 | Mediator of DNA damage checkpoint 1. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.764 |
| NFIA | GATA4 | ENSPANP00000031305 | ENSPANP00000006452 | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | GATA binding protein 4. | 0.680 |
| NFIA | GATA6 | ENSPANP00000031305 | ENSPANP00000003815 | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | GATA binding protein 6. | 0.666 |
| NFIA | NFIB | ENSPANP00000031305 | ENSPANP00000030927 | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.976 |
| NFIA | NFIC | ENSPANP00000031305 | ENSPANP00000031968 | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. | 0.779 |
