Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CTSSCathepsin S; Belongs to the peptidase C1 family. (331 aa)    
Predicted Functional Partners:
CTSL
Cathepsin L; Belongs to the peptidase C1 family.
  
0.977
CTSB
Cathepsin B; Belongs to the peptidase C1 family.
  
0.976
BCL2
BCL2 apoptosis regulator.
     
 0.927
IL10RA
Interleukin 10 receptor subunit alpha.
   
 
 0.923
BID
BH3 interacting domain death agonist.
   
 
 0.914
BCL2L1
BCL2 like 1.
     
 0.910
IL10RB
Interleukin 10 receptor, beta (Predicted).
   
 
 0.901
CST3
Cystatin C; Belongs to the cystatin family.
   
 0.870
LY86
Lymphocyte antigen 86.
   
  
 0.869
TYROBP
TYRO protein tyrosine kinase binding protein.
   
  
 0.800
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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