STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC3HECT domain-containing protein. (1050 aa)    
Predicted Functional Partners:
ISG15
ISG15 ubiquitin like modifier.
   
 0.788
TRIP12
Thyroid hormone receptor interactor 12.
   
 
0.606
SNX13
Sorting nexin 13.
      
 0.579
NAP1L5
Nucleosome assembly protein 1 like 5; Belongs to the nucleosome assembly protein (NAP) family.
      
 0.568
ZMIZ1
Zinc finger MIZ-type containing 1.
    
 
 0.566
RAB40C
RAB40C, member RAS oncogene family (Predicted).
      
 0.565
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.516
FAM13A
Family with sequence similarity 13 member A.
      
 0.501
CHRAC1
Chromatin accessibility complex subunit 1.
   
  
 0.486
MYPN
Myopalladin.
      
 0.477
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.