| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSH1 | EPO | ENSPANP00000016458 | ENSPANP00000003883 | Uncharacterized protein. | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | 0.906 |
| CSH1 | GH1 | ENSPANP00000016458 | ENSPANP00000016459 | Uncharacterized protein. | Uncharacterized protein. | 0.901 |
| CSH1 | GHR | ENSPANP00000016458 | ENSPANP00000000849 | Uncharacterized protein. | Growth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). | 0.988 |
| CSH1 | GHV | ENSPANP00000016458 | ENSPANP00000016457 | Uncharacterized protein. | Uncharacterized protein. | 0.901 |
| CSH1 | LEP | ENSPANP00000016458 | ENSPANP00000004103 | Uncharacterized protein. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.912 |
| CSH1 | LOC100999056 | ENSPANP00000016458 | ENSPANP00000028709 | Uncharacterized protein. | Uncharacterized protein. | 0.900 |
| CSH1 | LOC110741552 | ENSPANP00000016458 | ENSPANP00000047701 | Uncharacterized protein. | Uncharacterized protein. | 0.901 |
| CSH1 | PRL | ENSPANP00000016458 | ENSPANP00000013755 | Uncharacterized protein. | Prolactin. | 0.971 |
| CSH1 | PRLR | ENSPANP00000016458 | ENSPANP00000001406 | Uncharacterized protein. | Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin. | 0.802 |
| CSH1 | THPO | ENSPANP00000016458 | ENSPANP00000009076 | Uncharacterized protein. | Thrombopoietin. | 0.900 |
| EPO | CSH1 | ENSPANP00000003883 | ENSPANP00000016458 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Uncharacterized protein. | 0.906 |
| EPO | GH1 | ENSPANP00000003883 | ENSPANP00000016459 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Uncharacterized protein. | 0.906 |
| EPO | GHR | ENSPANP00000003883 | ENSPANP00000000849 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Growth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). | 0.666 |
| EPO | GHV | ENSPANP00000003883 | ENSPANP00000016457 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Uncharacterized protein. | 0.906 |
| EPO | LEP | ENSPANP00000003883 | ENSPANP00000004103 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.950 |
| EPO | LOC100999056 | ENSPANP00000003883 | ENSPANP00000028709 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Uncharacterized protein. | 0.906 |
| EPO | LOC110741552 | ENSPANP00000003883 | ENSPANP00000047701 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Uncharacterized protein. | 0.906 |
| EPO | PRL | ENSPANP00000003883 | ENSPANP00000013755 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Prolactin. | 0.911 |
| EPO | THPO | ENSPANP00000003883 | ENSPANP00000009076 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. | Thrombopoietin. | 0.957 |
| GH1 | CSH1 | ENSPANP00000016459 | ENSPANP00000016458 | Uncharacterized protein. | Uncharacterized protein. | 0.901 |
