| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APPL1 | APPL2 | ENSPANP00000035855 | ENSPANP00000010536 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. | 0.915 |
| APPL1 | IGDCC3 | ENSPANP00000035855 | ENSPANP00000014145 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. | Immunoglobulin superfamily DCC subclass member 3. | 0.905 |
| APPL2 | APPL1 | ENSPANP00000010536 | ENSPANP00000035855 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. | 0.915 |
| APPL2 | IGDCC3 | ENSPANP00000010536 | ENSPANP00000014145 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. | Immunoglobulin superfamily DCC subclass member 3. | 0.905 |
| DRAXIN | IGDCC3 | ENSPANP00000003106 | ENSPANP00000014145 | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. | Immunoglobulin superfamily DCC subclass member 3. | 0.536 |
| DRAXIN | NTN3 | ENSPANP00000003106 | ENSPANP00000013715 | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. | Netrin 3. | 0.797 |
| DRAXIN | NTN5 | ENSPANP00000003106 | ENSPANP00000004714 | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. | Netrin 5. | 0.762 |
| DRAXIN | NTNG1 | ENSPANP00000003106 | ENSPANP00000018694 | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. | Netrin G1. | 0.466 |
| DRAXIN | NTNG2 | ENSPANP00000003106 | ENSPANP00000018819 | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. | Netrin G2. | 0.445 |
| IGDCC3 | APPL1 | ENSPANP00000014145 | ENSPANP00000035855 | Immunoglobulin superfamily DCC subclass member 3. | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. | 0.905 |
| IGDCC3 | APPL2 | ENSPANP00000014145 | ENSPANP00000010536 | Immunoglobulin superfamily DCC subclass member 3. | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. | 0.905 |
| IGDCC3 | DRAXIN | ENSPANP00000014145 | ENSPANP00000003106 | Immunoglobulin superfamily DCC subclass member 3. | Draxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. | 0.536 |
| IGDCC3 | KALRN | ENSPANP00000014145 | ENSPANP00000005411 | Immunoglobulin superfamily DCC subclass member 3. | Kalirin RhoGEF kinase. | 0.555 |
| IGDCC3 | NTN3 | ENSPANP00000014145 | ENSPANP00000013715 | Immunoglobulin superfamily DCC subclass member 3. | Netrin 3. | 0.638 |
| IGDCC3 | NTN5 | ENSPANP00000014145 | ENSPANP00000004714 | Immunoglobulin superfamily DCC subclass member 3. | Netrin 5. | 0.638 |
| IGDCC3 | NTNG1 | ENSPANP00000014145 | ENSPANP00000018694 | Immunoglobulin superfamily DCC subclass member 3. | Netrin G1. | 0.670 |
| IGDCC3 | NTNG2 | ENSPANP00000014145 | ENSPANP00000018819 | Immunoglobulin superfamily DCC subclass member 3. | Netrin G2. | 0.638 |
| IGDCC3 | PTK2B | ENSPANP00000014145 | ENSPANP00000001487 | Immunoglobulin superfamily DCC subclass member 3. | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.533 |
| IGDCC3 | TRIO | ENSPANP00000014145 | ENSPANP00000030703 | Immunoglobulin superfamily DCC subclass member 3. | Trio Rho guanine nucleotide exchange factor. | 0.555 |
| KALRN | IGDCC3 | ENSPANP00000005411 | ENSPANP00000014145 | Kalirin RhoGEF kinase. | Immunoglobulin superfamily DCC subclass member 3. | 0.555 |
