| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGO2 | DGCR8 | ENSPANP00000047416 | ENSPANP00000015194 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | DGCR8 microprocessor complex subunit. | 0.818 |
| AGO2 | DICER1 | ENSPANP00000047416 | ENSPANP00000013158 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.994 |
| AGO2 | DROSHA | ENSPANP00000047416 | ENSPANP00000009748 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Drosha ribonuclease III. | 0.883 |
| AGO2 | MRPL44 | ENSPANP00000047416 | ENSPANP00000022138 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Mitochondrial ribosomal protein L44. | 0.670 |
| AGO2 | TARBP2 | ENSPANP00000047416 | ENSPANP00000012072 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] | 0.989 |
| AGO2 | XPO5 | ENSPANP00000047416 | ENSPANP00000012768 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | Exportin 5. | 0.824 |
| DDX17 | DDX5 | ENSPANP00000013327 | ENSPANP00000028858 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | 0.995 |
| DDX17 | DGCR8 | ENSPANP00000013327 | ENSPANP00000015194 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | DGCR8 microprocessor complex subunit. | 0.790 |
| DDX17 | DROSHA | ENSPANP00000013327 | ENSPANP00000009748 | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | Drosha ribonuclease III. | 0.904 |
| DDX5 | DDX17 | ENSPANP00000028858 | ENSPANP00000013327 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | 0.995 |
| DDX5 | DGCR8 | ENSPANP00000028858 | ENSPANP00000015194 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | DGCR8 microprocessor complex subunit. | 0.800 |
| DDX5 | DROSHA | ENSPANP00000028858 | ENSPANP00000009748 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | Drosha ribonuclease III. | 0.986 |
| DGCR8 | AGO2 | ENSPANP00000015194 | ENSPANP00000047416 | DGCR8 microprocessor complex subunit. | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] | 0.818 |
| DGCR8 | DDX17 | ENSPANP00000015194 | ENSPANP00000013327 | DGCR8 microprocessor complex subunit. | DEAD-box helicase 17; Belongs to the DEAD box helicase family. | 0.790 |
| DGCR8 | DDX5 | ENSPANP00000015194 | ENSPANP00000028858 | DGCR8 microprocessor complex subunit. | DEAD-box helicase 5; Belongs to the DEAD box helicase family. | 0.800 |
| DGCR8 | DICER1 | ENSPANP00000015194 | ENSPANP00000013158 | DGCR8 microprocessor complex subunit. | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. | 0.942 |
| DGCR8 | DROSHA | ENSPANP00000015194 | ENSPANP00000009748 | DGCR8 microprocessor complex subunit. | Drosha ribonuclease III. | 0.998 |
| DGCR8 | MDC1 | ENSPANP00000015194 | ENSPANP00000013959 | DGCR8 microprocessor complex subunit. | Mediator of DNA damage checkpoint 1. | 0.756 |
| DGCR8 | MRPL44 | ENSPANP00000015194 | ENSPANP00000022138 | DGCR8 microprocessor complex subunit. | Mitochondrial ribosomal protein L44. | 0.859 |
| DGCR8 | TARBP2 | ENSPANP00000015194 | ENSPANP00000012072 | DGCR8 microprocessor complex subunit. | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] | 0.747 |
