EXT1 protein (Papio anubis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EXT1

Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity). (746 aa)

Predicted Functional Partners:

EXT2

0.993

EXTL2

0.864

EXTL3

0.668

SDC1

0.611

XYLT2

0.574

GLCE

0.563

SDC3

0.537

GPC1

0.523

NDST1

0.497

GPC5

0.497

Your Current Organism:

Papio anubis

NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EXT1	EXT2	ENSPANP00000015323	ENSPANP00000004695	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	0.993
EXT1	EXTL2	ENSPANP00000015323	ENSPANP00000033287	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	Exostosin like glycosyltransferase 2.	0.864
EXT1	EXTL3	ENSPANP00000015323	ENSPANP00000018075	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.	0.668
EXT1	GLCE	ENSPANP00000015323	ENSPANP00000014198	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	Glucuronic acid epimerase.	0.563
EXT1	GPC1	ENSPANP00000015323	ENSPANP00000011435	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.523
EXT1	GPC5	ENSPANP00000015323	ENSPANP00000005121	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.497
EXT1	NDST1	ENSPANP00000015323	ENSPANP00000004214	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	N-deacetylase and N-sulfotransferase 1.	0.497
EXT1	SDC1	ENSPANP00000015323	ENSPANP00000012315	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.611
EXT1	SDC3	ENSPANP00000015323	ENSPANP00000036358	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.537
EXT1	XYLT2	ENSPANP00000015323	ENSPANP00000020251	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	Xylosyltransferase 2.	0.574
EXT2	EXT1	ENSPANP00000004695	ENSPANP00000015323	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	0.993
EXT2	EXTL3	ENSPANP00000004695	ENSPANP00000018075	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.	0.618
EXT2	GPC1	ENSPANP00000004695	ENSPANP00000011435	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.530
EXT2	GPC5	ENSPANP00000004695	ENSPANP00000005121	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family.	0.577
EXT2	NDST1	ENSPANP00000004695	ENSPANP00000004214	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	N-deacetylase and N-sulfotransferase 1.	0.517
EXT2	SDC1	ENSPANP00000004695	ENSPANP00000012315	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.579
EXT2	SDC3	ENSPANP00000004695	ENSPANP00000036358	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.567
EXT2	XYLT2	ENSPANP00000004695	ENSPANP00000020251	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	Xylosyltransferase 2.	0.624
EXTL2	EXT1	ENSPANP00000033287	ENSPANP00000015323	Exostosin like glycosyltransferase 2.	Exostosin-1; Glycosyltransferase required for the biosynthesis of heparan- sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Required for the exosomal release of SDCBP, CD63 and syndecan (By similarity).	0.864
EXTL2	EXTL3	ENSPANP00000033287	ENSPANP00000018075	Exostosin like glycosyltransferase 2.	Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.	0.912

page 1 of 4

Server load: low (22%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2023

Credits

Access

Info

About