node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGFR | FLT3 | ENSPANP00000003878 | ENSPANP00000033119 | Receptor protein-tyrosine kinase. | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.529 |
EGFR | PDGFA | ENSPANP00000003878 | ENSPANP00000020222 | Receptor protein-tyrosine kinase. | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. | 0.918 |
EGFR | PDGFB | ENSPANP00000003878 | ENSPANP00000013359 | Receptor protein-tyrosine kinase. | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | 0.924 |
EGFR | PDGFC | ENSPANP00000003878 | ENSPANP00000015374 | Receptor protein-tyrosine kinase. | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.917 |
EGFR | PDGFD | ENSPANP00000003878 | ENSPANP00000005336 | Receptor protein-tyrosine kinase. | Platelet derived growth factor D. | 0.900 |
EGFR | PDGFRA | ENSPANP00000003878 | ENSPANP00000007029 | Receptor protein-tyrosine kinase. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.935 |
EGFR | PDGFRB | ENSPANP00000003878 | ENSPANP00000007796 | Receptor protein-tyrosine kinase. | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. | 0.963 |
EGFR | VEGFB | ENSPANP00000003878 | ENSPANP00000011047 | Receptor protein-tyrosine kinase. | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. | 0.770 |
EGFR | VEGFC | ENSPANP00000003878 | ENSPANP00000009134 | Receptor protein-tyrosine kinase. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.782 |
EGFR | VEGFD | ENSPANP00000003878 | ENSPANP00000006013 | Receptor protein-tyrosine kinase. | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. | 0.803 |
FLT3 | EGFR | ENSPANP00000033119 | ENSPANP00000003878 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Receptor protein-tyrosine kinase. | 0.529 |
FLT3 | PDGFA | ENSPANP00000033119 | ENSPANP00000020222 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. | 0.888 |
FLT3 | PDGFB | ENSPANP00000033119 | ENSPANP00000013359 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. | 0.941 |
FLT3 | PDGFC | ENSPANP00000033119 | ENSPANP00000015374 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.928 |
FLT3 | PDGFD | ENSPANP00000033119 | ENSPANP00000005336 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet derived growth factor D. | 0.904 |
FLT3 | PDGFRB | ENSPANP00000033119 | ENSPANP00000007796 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. | 0.726 |
FLT3 | VEGFB | ENSPANP00000033119 | ENSPANP00000011047 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. | 0.839 |
FLT3 | VEGFC | ENSPANP00000033119 | ENSPANP00000009134 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.910 |
FLT3 | VEGFD | ENSPANP00000033119 | ENSPANP00000006013 | Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. | 0.882 |
PDGFA | EGFR | ENSPANP00000020222 | ENSPANP00000003878 | Platelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. | Receptor protein-tyrosine kinase. | 0.918 |