STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOTCH1Notch receptor 1. (2541 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.997
MAML1
Mastermind like transcriptional coactivator 1.
    
 0.996
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.992
JAG2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.990
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.984
NCSTN
Nicastrin.
    
 0.984
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.983
PSEN1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.980
PSEN2
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.979
APH1A
Aph-1 homolog A, gamma-secretase subunit.
    
 0.971
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.