| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HGS | STAM | ENSPANP00000024190 | ENSPANP00000019947 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule. | 0.999 |
| HGS | STAM2 | ENSPANP00000024190 | ENSPANP00000017923 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Signal transducing adaptor molecule 2. | 0.999 |
| HGS | TSG101 | ENSPANP00000024190 | ENSPANP00000029768 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Tumor susceptibility 101. | 0.998 |
| HGS | USP8 | ENSPANP00000024190 | ENSPANP00000014036 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. | 0.976 |
| HGS | VPS37A | ENSPANP00000024190 | ENSPANP00000005196 | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] | VPS37A subunit of ESCRT-I. | 0.913 |
| JAK1 | JAK2 | ENSPANP00000022669 | ENSPANP00000047613 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.997 |
| JAK1 | JAK3 | ENSPANP00000022669 | ENSPANP00000006068 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.997 |
| JAK1 | STAM | ENSPANP00000022669 | ENSPANP00000019947 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.924 |
| JAK1 | STAM2 | ENSPANP00000022669 | ENSPANP00000017923 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.969 |
| JAK1 | TYK2 | ENSPANP00000022669 | ENSPANP00000000072 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.975 |
| JAK2 | JAK1 | ENSPANP00000047613 | ENSPANP00000022669 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.997 |
| JAK2 | JAK3 | ENSPANP00000047613 | ENSPANP00000006068 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.960 |
| JAK2 | STAM | ENSPANP00000047613 | ENSPANP00000019947 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.955 |
| JAK2 | STAM2 | ENSPANP00000047613 | ENSPANP00000017923 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.945 |
| JAK2 | TYK2 | ENSPANP00000047613 | ENSPANP00000000072 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.984 |
| JAK3 | JAK1 | ENSPANP00000006068 | ENSPANP00000022669 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.997 |
| JAK3 | JAK2 | ENSPANP00000006068 | ENSPANP00000047613 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.960 |
| JAK3 | STAM | ENSPANP00000006068 | ENSPANP00000019947 | Tyrosine-protein kinase. | Signal transducing adaptor molecule. | 0.953 |
| JAK3 | STAM2 | ENSPANP00000006068 | ENSPANP00000017923 | Tyrosine-protein kinase. | Signal transducing adaptor molecule 2. | 0.958 |
| JAK3 | TYK2 | ENSPANP00000006068 | ENSPANP00000000072 | Tyrosine-protein kinase. | Tyrosine-protein kinase. | 0.952 |
