| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SMAD2 | SMAD3 | ENSPANP00000037043 | ENSPANP00000014165 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD2 | SMAD4 | ENSPANP00000037043 | ENSPANP00000006643 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD2 | SMAD7 | ENSPANP00000037043 | ENSPANP00000005066 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.992 |
| SMAD2 | SMURF1 | ENSPANP00000037043 | ENSPANP00000018770 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.932 |
| SMAD2 | SMURF2 | ENSPANP00000037043 | ENSPANP00000031635 | Mothers against decapentaplegic homolog. | SMAD specific E3 ubiquitin protein ligase 2. | 0.991 |
| SMAD2 | TGFB1 | ENSPANP00000037043 | ENSPANP00000004153 | Mothers against decapentaplegic homolog. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.901 |
| SMAD2 | TGFB2 | ENSPANP00000037043 | ENSPANP00000004840 | Mothers against decapentaplegic homolog. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.740 |
| SMAD2 | TGFB3 | ENSPANP00000037043 | ENSPANP00000015880 | Mothers against decapentaplegic homolog. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.710 |
| SMAD2 | TGFBR1 | ENSPANP00000037043 | ENSPANP00000046935 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.998 |
| SMAD2 | TGFBR2 | ENSPANP00000037043 | ENSPANP00000005982 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.987 |
| SMAD3 | SMAD2 | ENSPANP00000014165 | ENSPANP00000037043 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD3 | SMAD4 | ENSPANP00000014165 | ENSPANP00000006643 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.999 |
| SMAD3 | SMAD7 | ENSPANP00000014165 | ENSPANP00000005066 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.992 |
| SMAD3 | SMURF1 | ENSPANP00000014165 | ENSPANP00000018770 | Mothers against decapentaplegic homolog. | E3 ubiquitin-protein ligase. | 0.952 |
| SMAD3 | SMURF2 | ENSPANP00000014165 | ENSPANP00000031635 | Mothers against decapentaplegic homolog. | SMAD specific E3 ubiquitin protein ligase 2. | 0.987 |
| SMAD3 | TGFB1 | ENSPANP00000014165 | ENSPANP00000004153 | Mothers against decapentaplegic homolog. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.908 |
| SMAD3 | TGFB2 | ENSPANP00000014165 | ENSPANP00000004840 | Mothers against decapentaplegic homolog. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.769 |
| SMAD3 | TGFB3 | ENSPANP00000014165 | ENSPANP00000015880 | Mothers against decapentaplegic homolog. | Transforming growth factor beta; Belongs to the TGF-beta family. | 0.701 |
| SMAD3 | TGFBR1 | ENSPANP00000014165 | ENSPANP00000046935 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.997 |
| SMAD3 | TGFBR2 | ENSPANP00000014165 | ENSPANP00000005982 | Mothers against decapentaplegic homolog. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.985 |
