| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| B2M | BLM | ENSPANP00000013995 | ENSPANP00000014473 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | BLM RecQ like helicase. | 0.805 |
| B2M | CLSPN | ENSPANP00000013995 | ENSPANP00000017837 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | Claspin. | 0.799 |
| B2M | ENSPANP00000019650 | ENSPANP00000013995 | ENSPANP00000019650 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | Uncharacterized protein. | 0.880 |
| B2M | POLD1 | ENSPANP00000013995 | ENSPANP00000008432 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | DNA polymerase. | 0.827 |
| B2M | RPA1 | ENSPANP00000013995 | ENSPANP00000019489 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.949 |
| B2M | TOP3A | ENSPANP00000013995 | ENSPANP00000019759 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.828 |
| B2M | WRN | ENSPANP00000013995 | ENSPANP00000018132 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | WRN RecQ like helicase. | 0.860 |
| B2M | XPA | ENSPANP00000013995 | ENSPANP00000019060 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | XPA, DNA damage recognition and repair factor. | 0.841 |
| BLM | B2M | ENSPANP00000014473 | ENSPANP00000013995 | BLM RecQ like helicase. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | 0.805 |
| BLM | CLSPN | ENSPANP00000014473 | ENSPANP00000017837 | BLM RecQ like helicase. | Claspin. | 0.738 |
| BLM | ENSPANP00000019650 | ENSPANP00000014473 | ENSPANP00000019650 | BLM RecQ like helicase. | Uncharacterized protein. | 0.862 |
| BLM | ENSPANP00000030504 | ENSPANP00000014473 | ENSPANP00000030504 | BLM RecQ like helicase. | RPA_C domain-containing protein. | 0.855 |
| BLM | POLD1 | ENSPANP00000014473 | ENSPANP00000008432 | BLM RecQ like helicase. | DNA polymerase. | 0.726 |
| BLM | RPA1 | ENSPANP00000014473 | ENSPANP00000019489 | BLM RecQ like helicase. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.995 |
| BLM | RPA2 | ENSPANP00000014473 | ENSPANP00000027721 | BLM RecQ like helicase. | Replication protein A2. | 0.989 |
| BLM | TOP3A | ENSPANP00000014473 | ENSPANP00000019759 | BLM RecQ like helicase. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.999 |
| BLM | WRN | ENSPANP00000014473 | ENSPANP00000018132 | BLM RecQ like helicase. | WRN RecQ like helicase. | 0.607 |
| CLSPN | B2M | ENSPANP00000017837 | ENSPANP00000013995 | Claspin. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). | 0.799 |
| CLSPN | BLM | ENSPANP00000017837 | ENSPANP00000014473 | Claspin. | BLM RecQ like helicase. | 0.738 |
| CLSPN | ENSPANP00000019650 | ENSPANP00000017837 | ENSPANP00000019650 | Claspin. | Uncharacterized protein. | 0.872 |
