| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ESR1 | ESR2 | ENSPANP00000015224 | ENSPANP00000017082 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Uncharacterized protein. | 0.999 |
| ESR1 | HDAC3 | ENSPANP00000015224 | ENSPANP00000001672 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.723 |
| ESR1 | NCOR1 | ENSPANP00000015224 | ENSPANP00000019731 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor corepressor 1. | 0.996 |
| ESR1 | NCOR2 | ENSPANP00000015224 | ENSPANP00000029106 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor corepressor 2. | 0.931 |
| ESR1 | SIN3A | ENSPANP00000015224 | ENSPANP00000009527 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | SIN3 transcription regulator family member A. | 0.431 |
| ESR2 | ESR1 | ENSPANP00000017082 | ENSPANP00000015224 | Uncharacterized protein. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.999 |
| ESR2 | HDAC3 | ENSPANP00000017082 | ENSPANP00000001672 | Uncharacterized protein. | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | 0.487 |
| ESR2 | NCOR1 | ENSPANP00000017082 | ENSPANP00000019731 | Uncharacterized protein. | Nuclear receptor corepressor 1. | 0.980 |
| ESR2 | NCOR2 | ENSPANP00000017082 | ENSPANP00000029106 | Uncharacterized protein. | Nuclear receptor corepressor 2. | 0.829 |
| HDAC3 | ESR1 | ENSPANP00000001672 | ENSPANP00000015224 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.723 |
| HDAC3 | ESR2 | ENSPANP00000001672 | ENSPANP00000017082 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Uncharacterized protein. | 0.487 |
| HDAC3 | NCOR1 | ENSPANP00000001672 | ENSPANP00000019731 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Nuclear receptor corepressor 1. | 0.999 |
| HDAC3 | NCOR2 | ENSPANP00000001672 | ENSPANP00000029106 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Nuclear receptor corepressor 2. | 0.991 |
| HDAC3 | PPARG | ENSPANP00000001672 | ENSPANP00000043034 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.937 |
| HDAC3 | RXRA | ENSPANP00000001672 | ENSPANP00000032125 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Retinoid X receptor alpha. | 0.822 |
| HDAC3 | SIN3A | ENSPANP00000001672 | ENSPANP00000009527 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | SIN3 transcription regulator family member A. | 0.966 |
| HDAC3 | SKI | ENSPANP00000001672 | ENSPANP00000015071 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | SKI proto-oncogene. | 0.830 |
| HDAC3 | THRA | ENSPANP00000001672 | ENSPANP00000028719 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Thyroid hormone receptor alpha. | 0.882 |
| HDAC3 | THRB | ENSPANP00000001672 | ENSPANP00000045220 | Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. | Thyroid hormone receptor beta. | 0.801 |
| NCOR1 | ESR1 | ENSPANP00000019731 | ENSPANP00000015224 | Nuclear receptor corepressor 1. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.996 |
