node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FZD8 | LRP5 | ENSPANP00000020143 | ENSPANP00000030384 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.928 |
FZD8 | LRP6 | ENSPANP00000020143 | ENSPANP00000007522 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.949 |
FZD8 | RNF43 | ENSPANP00000020143 | ENSPANP00000020367 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | RING-type domain-containing protein. | 0.916 |
FZD8 | ROR1 | ENSPANP00000020143 | ENSPANP00000022920 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. | 0.913 |
FZD8 | WNT1 | ENSPANP00000020143 | ENSPANP00000018339 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.953 |
FZD8 | WNT11 | ENSPANP00000020143 | ENSPANP00000006878 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.953 |
FZD8 | WNT3 | ENSPANP00000020143 | ENSPANP00000020851 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.954 |
FZD8 | WNT5A | ENSPANP00000020143 | ENSPANP00000005288 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.948 |
FZD8 | WNT5B | ENSPANP00000020143 | ENSPANP00000008904 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.952 |
FZD8 | WNT8A | ENSPANP00000020143 | ENSPANP00000006909 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.916 |
LRP5 | FZD8 | ENSPANP00000030384 | ENSPANP00000020143 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.928 |
LRP5 | LRP6 | ENSPANP00000030384 | ENSPANP00000007522 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.960 |
LRP5 | RNF43 | ENSPANP00000030384 | ENSPANP00000020367 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | RING-type domain-containing protein. | 0.674 |
LRP5 | ROR1 | ENSPANP00000030384 | ENSPANP00000022920 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. | 0.439 |
LRP5 | WNT1 | ENSPANP00000030384 | ENSPANP00000018339 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.913 |
LRP5 | WNT11 | ENSPANP00000030384 | ENSPANP00000006878 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.858 |
LRP5 | WNT3 | ENSPANP00000030384 | ENSPANP00000020851 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.884 |
LRP5 | WNT5A | ENSPANP00000030384 | ENSPANP00000005288 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.886 |
LRP5 | WNT5B | ENSPANP00000030384 | ENSPANP00000008904 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.830 |
LRP5 | WNT8A | ENSPANP00000030384 | ENSPANP00000006909 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.829 |