| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BARD1 | BLM | ENSPANP00000005319 | ENSPANP00000014473 | BRCA1 associated RING domain 1. | BLM RecQ like helicase. | 0.766 |
| BARD1 | BRCA1 | ENSPANP00000005319 | ENSPANP00000027226 | BRCA1 associated RING domain 1. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.999 |
| BARD1 | BRCA2 | ENSPANP00000005319 | ENSPANP00000022490 | BRCA1 associated RING domain 1. | BRCA2 DNA repair associated. | 0.984 |
| BARD1 | BRIP1 | ENSPANP00000005319 | ENSPANP00000020408 | BRCA1 associated RING domain 1. | BRCA1 interacting protein C-terminal helicase 1. | 0.984 |
| BARD1 | MLH1 | ENSPANP00000005319 | ENSPANP00000003232 | BRCA1 associated RING domain 1. | MutL homolog 1. | 0.744 |
| BARD1 | MRE11 | ENSPANP00000005319 | ENSPANP00000009957 | BRCA1 associated RING domain 1. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.975 |
| BARD1 | NBN | ENSPANP00000005319 | ENSPANP00000015046 | BRCA1 associated RING domain 1. | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. | 0.979 |
| BARD1 | PALB2 | ENSPANP00000005319 | ENSPANP00000012404 | BRCA1 associated RING domain 1. | Partner and localizer of BRCA2. | 0.910 |
| BARD1 | PMS2 | ENSPANP00000005319 | ENSPANP00000003983 | BRCA1 associated RING domain 1. | PMS1 homolog 2, mismatch repair system component. | 0.499 |
| BARD1 | TOPBP1 | ENSPANP00000005319 | ENSPANP00000006180 | BRCA1 associated RING domain 1. | DNA topoisomerase II binding protein 1. | 0.978 |
| BLM | BARD1 | ENSPANP00000014473 | ENSPANP00000005319 | BLM RecQ like helicase. | BRCA1 associated RING domain 1. | 0.766 |
| BLM | BRCA1 | ENSPANP00000014473 | ENSPANP00000027226 | BLM RecQ like helicase. | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] | 0.951 |
| BLM | BRCA2 | ENSPANP00000014473 | ENSPANP00000022490 | BLM RecQ like helicase. | BRCA2 DNA repair associated. | 0.896 |
| BLM | BRIP1 | ENSPANP00000014473 | ENSPANP00000020408 | BLM RecQ like helicase. | BRCA1 interacting protein C-terminal helicase 1. | 0.910 |
| BLM | MLH1 | ENSPANP00000014473 | ENSPANP00000003232 | BLM RecQ like helicase. | MutL homolog 1. | 0.956 |
| BLM | MRE11 | ENSPANP00000014473 | ENSPANP00000009957 | BLM RecQ like helicase. | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. | 0.949 |
| BLM | NBN | ENSPANP00000014473 | ENSPANP00000015046 | BLM RecQ like helicase. | Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. | 0.945 |
| BLM | PALB2 | ENSPANP00000014473 | ENSPANP00000012404 | BLM RecQ like helicase. | Partner and localizer of BRCA2. | 0.747 |
| BLM | PMS2 | ENSPANP00000014473 | ENSPANP00000003983 | BLM RecQ like helicase. | PMS1 homolog 2, mismatch repair system component. | 0.452 |
| BLM | TOPBP1 | ENSPANP00000014473 | ENSPANP00000006180 | BLM RecQ like helicase. | DNA topoisomerase II binding protein 1. | 0.904 |
