| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCNA1 | CCNA2 | ENSPANP00000011361 | ENSPANP00000015078 | Cyclin A1; Belongs to the cyclin family. | Cyclin A2; Belongs to the cyclin family. | 0.994 |
| CCNA1 | CDC6 | ENSPANP00000011361 | ENSPANP00000020590 | Cyclin A1; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.998 |
| CCNA1 | CDT1 | ENSPANP00000011361 | ENSPANP00000001170 | Cyclin A1; Belongs to the cyclin family. | Chromatin licensing and DNA replication factor 1. | 0.975 |
| CCNA1 | MCM10 | ENSPANP00000011361 | ENSPANP00000047494 | Cyclin A1; Belongs to the cyclin family. | Minichromosome maintenance 10 replication initiation factor. | 0.795 |
| CCNA1 | MCM2 | ENSPANP00000011361 | ENSPANP00000004650 | Cyclin A1; Belongs to the cyclin family. | DNA helicase; Belongs to the MCM family. | 0.795 |
| CCNA1 | MCM3 | ENSPANP00000011361 | ENSPANP00000012989 | Cyclin A1; Belongs to the cyclin family. | DNA helicase; Belongs to the MCM family. | 0.807 |
| CCNA1 | MCM7 | ENSPANP00000011361 | ENSPANP00000009605 | Cyclin A1; Belongs to the cyclin family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.905 |
| CCNA1 | ORC1 | ENSPANP00000011361 | ENSPANP00000000718 | Cyclin A1; Belongs to the cyclin family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.964 |
| CCNA1 | ORC3 | ENSPANP00000011361 | ENSPANP00000005254 | Cyclin A1; Belongs to the cyclin family. | Origin recognition complex subunit 3. | 0.669 |
| CCNA1 | ORC6 | ENSPANP00000011361 | ENSPANP00000012615 | Cyclin A1; Belongs to the cyclin family. | Origin recognition complex subunit 6. | 0.655 |
| CCNA2 | CCNA1 | ENSPANP00000015078 | ENSPANP00000011361 | Cyclin A2; Belongs to the cyclin family. | Cyclin A1; Belongs to the cyclin family. | 0.994 |
| CCNA2 | CDC6 | ENSPANP00000015078 | ENSPANP00000020590 | Cyclin A2; Belongs to the cyclin family. | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. | 0.998 |
| CCNA2 | CDT1 | ENSPANP00000015078 | ENSPANP00000001170 | Cyclin A2; Belongs to the cyclin family. | Chromatin licensing and DNA replication factor 1. | 0.986 |
| CCNA2 | MCM10 | ENSPANP00000015078 | ENSPANP00000047494 | Cyclin A2; Belongs to the cyclin family. | Minichromosome maintenance 10 replication initiation factor. | 0.815 |
| CCNA2 | MCM2 | ENSPANP00000015078 | ENSPANP00000004650 | Cyclin A2; Belongs to the cyclin family. | DNA helicase; Belongs to the MCM family. | 0.800 |
| CCNA2 | MCM3 | ENSPANP00000015078 | ENSPANP00000012989 | Cyclin A2; Belongs to the cyclin family. | DNA helicase; Belongs to the MCM family. | 0.827 |
| CCNA2 | MCM7 | ENSPANP00000015078 | ENSPANP00000009605 | Cyclin A2; Belongs to the cyclin family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.907 |
| CCNA2 | ORC1 | ENSPANP00000015078 | ENSPANP00000000718 | Cyclin A2; Belongs to the cyclin family. | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. | 0.982 |
| CCNA2 | ORC3 | ENSPANP00000015078 | ENSPANP00000005254 | Cyclin A2; Belongs to the cyclin family. | Origin recognition complex subunit 3. | 0.605 |
| CCNA2 | ORC6 | ENSPANP00000015078 | ENSPANP00000012615 | Cyclin A2; Belongs to the cyclin family. | Origin recognition complex subunit 6. | 0.645 |
