| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DKK1 | LRP2 | ENSPANP00000042321 | ENSPANP00000018439 | Dickkopf WNT signaling pathway inhibitor 1. | LDL receptor related protein 2. | 0.672 |
| DKK1 | LRP4 | ENSPANP00000042321 | ENSPANP00000039963 | Dickkopf WNT signaling pathway inhibitor 1. | LDL receptor related protein 4. | 0.687 |
| DKK1 | LRP5 | ENSPANP00000042321 | ENSPANP00000030384 | Dickkopf WNT signaling pathway inhibitor 1. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.997 |
| DKK1 | LRP6 | ENSPANP00000042321 | ENSPANP00000007522 | Dickkopf WNT signaling pathway inhibitor 1. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.997 |
| DKK1 | SOST | ENSPANP00000042321 | ENSPANP00000020759 | Dickkopf WNT signaling pathway inhibitor 1. | Sclerostin. | 0.669 |
| LRP2 | DKK1 | ENSPANP00000018439 | ENSPANP00000042321 | LDL receptor related protein 2. | Dickkopf WNT signaling pathway inhibitor 1. | 0.672 |
| LRP2 | SOST | ENSPANP00000018439 | ENSPANP00000020759 | LDL receptor related protein 2. | Sclerostin. | 0.751 |
| LRP4 | DKK1 | ENSPANP00000039963 | ENSPANP00000042321 | LDL receptor related protein 4. | Dickkopf WNT signaling pathway inhibitor 1. | 0.687 |
| LRP4 | SOST | ENSPANP00000039963 | ENSPANP00000020759 | LDL receptor related protein 4. | Sclerostin. | 0.827 |
| LRP5 | DKK1 | ENSPANP00000030384 | ENSPANP00000042321 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Dickkopf WNT signaling pathway inhibitor 1. | 0.997 |
| LRP5 | LRP6 | ENSPANP00000030384 | ENSPANP00000007522 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.991 |
| LRP5 | SOST | ENSPANP00000030384 | ENSPANP00000020759 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Sclerostin. | 0.996 |
| LRP6 | DKK1 | ENSPANP00000007522 | ENSPANP00000042321 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Dickkopf WNT signaling pathway inhibitor 1. | 0.997 |
| LRP6 | LRP5 | ENSPANP00000007522 | ENSPANP00000030384 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.991 |
| LRP6 | SOST | ENSPANP00000007522 | ENSPANP00000020759 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Sclerostin. | 0.998 |
| MEPE | PTH | ENSPANP00000044375 | ENSPANP00000011826 | Matrix extracellular phosphoglycoprotein. | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | 0.562 |
| MEPE | SOST | ENSPANP00000044375 | ENSPANP00000020759 | Matrix extracellular phosphoglycoprotein. | Sclerostin. | 0.675 |
| MTHFSD | SMIM12 | ENSPANP00000008196 | ENSPANP00000015842 | Methenyltetrahydrofolate synthetase domain containing. | Small integral membrane protein 12. | 0.884 |
| MTHFSD | SOST | ENSPANP00000008196 | ENSPANP00000020759 | Methenyltetrahydrofolate synthetase domain containing. | Sclerostin. | 0.666 |
| PTH | MEPE | ENSPANP00000011826 | ENSPANP00000044375 | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. | Matrix extracellular phosphoglycoprotein. | 0.562 |
