| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MAP2K1 | MAP2K2 | ENSPANP00000022054 | ENSPANP00000039137 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | 0.999 |
| MAP2K1 | MAPK1 | ENSPANP00000022054 | ENSPANP00000025866 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.997 |
| MAP2K1 | MAPK14 | ENSPANP00000022054 | ENSPANP00000012511 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase. | 0.967 |
| MAP2K1 | MAPK3 | ENSPANP00000022054 | ENSPANP00000012509 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.998 |
| MAP2K1 | TP53 | ENSPANP00000022054 | ENSPANP00000033477 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.434 |
| MAP2K2 | MAP2K1 | ENSPANP00000039137 | ENSPANP00000022054 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | 0.999 |
| MAP2K2 | MAPK1 | ENSPANP00000039137 | ENSPANP00000025866 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.996 |
| MAP2K2 | MAPK14 | ENSPANP00000039137 | ENSPANP00000012511 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase. | 0.968 |
| MAP2K2 | MAPK3 | ENSPANP00000039137 | ENSPANP00000012509 | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.993 |
| MAPK1 | MAP2K1 | ENSPANP00000025866 | ENSPANP00000022054 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | 0.997 |
| MAPK1 | MAP2K2 | ENSPANP00000025866 | ENSPANP00000039137 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. | 0.996 |
| MAPK1 | MAPK14 | ENSPANP00000025866 | ENSPANP00000012511 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase. | 0.993 |
| MAPK1 | MAPK3 | ENSPANP00000025866 | ENSPANP00000012509 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.999 |
| MAPK1 | PTPN7 | ENSPANP00000025866 | ENSPANP00000015315 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Protein tyrosine phosphatase non-receptor type 7. | 0.995 |
| MAPK1 | PTPRR | ENSPANP00000025866 | ENSPANP00000030358 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Protein tyrosine phosphatase receptor type R. | 0.993 |
| MAPK1 | RPS6KA1 | ENSPANP00000025866 | ENSPANP00000031130 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Ribosomal protein S6 kinase. | 0.995 |
| MAPK1 | RPS6KA2 | ENSPANP00000025866 | ENSPANP00000029808 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Ribosomal protein S6 kinase. | 0.995 |
| MAPK1 | RPS6KA3 | ENSPANP00000025866 | ENSPANP00000040202 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Ribosomal protein S6 kinase. | 0.995 |
| MAPK1 | TP53 | ENSPANP00000025866 | ENSPANP00000033477 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.994 |
| MAPK14 | MAP2K1 | ENSPANP00000012511 | ENSPANP00000022054 | Mitogen-activated protein kinase. | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. | 0.967 |
