| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| MED1 | NCOA1 | ENSPANP00000020534 | ENSPANP00000043481 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.730 |
| MED1 | NCOA2 | ENSPANP00000020534 | ENSPANP00000006814 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor coactivator. | 0.692 |
| MED1 | NR1H3 | ENSPANP00000020534 | ENSPANP00000038819 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor subfamily 1 group H member 3. | 0.729 |
| MED1 | PPARA | ENSPANP00000020534 | ENSPANP00000013577 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Peroxisome proliferator activated receptor alpha. | 0.943 |
| MED1 | PPARD | ENSPANP00000020534 | ENSPANP00000012484 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Peroxisome proliferator activated receptor delta. | 0.639 |
| MED1 | PPARG | ENSPANP00000020534 | ENSPANP00000043034 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.965 |
| MED1 | RARA | ENSPANP00000020534 | ENSPANP00000043544 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoic acid receptor alpha. | 0.931 |
| MED1 | RXRA | ENSPANP00000020534 | ENSPANP00000032125 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor alpha. | 0.985 |
| MED1 | RXRB | ENSPANP00000020534 | ENSPANP00000012407 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor beta. | 0.940 |
| MED1 | RXRG | ENSPANP00000020534 | ENSPANP00000004047 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor gamma. | 0.959 |
| NCOA1 | MED1 | ENSPANP00000043481 | ENSPANP00000020534 | Nuclear receptor coactivator. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.730 |
| NCOA1 | NCOA2 | ENSPANP00000043481 | ENSPANP00000006814 | Nuclear receptor coactivator. | Nuclear receptor coactivator. | 0.996 |
| NCOA1 | NR1H3 | ENSPANP00000043481 | ENSPANP00000038819 | Nuclear receptor coactivator. | Nuclear receptor subfamily 1 group H member 3. | 0.902 |
| NCOA1 | PPARA | ENSPANP00000043481 | ENSPANP00000013577 | Nuclear receptor coactivator. | Peroxisome proliferator activated receptor alpha. | 0.951 |
| NCOA1 | PPARD | ENSPANP00000043481 | ENSPANP00000012484 | Nuclear receptor coactivator. | Peroxisome proliferator activated receptor delta. | 0.866 |
| NCOA1 | PPARG | ENSPANP00000043481 | ENSPANP00000043034 | Nuclear receptor coactivator. | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] | 0.956 |
| NCOA1 | RARA | ENSPANP00000043481 | ENSPANP00000043544 | Nuclear receptor coactivator. | Retinoic acid receptor alpha. | 0.921 |
| NCOA1 | RXRA | ENSPANP00000043481 | ENSPANP00000032125 | Nuclear receptor coactivator. | Retinoid X receptor alpha. | 0.992 |
| NCOA1 | RXRB | ENSPANP00000043481 | ENSPANP00000012407 | Nuclear receptor coactivator. | Retinoid X receptor beta. | 0.928 |
| NCOA1 | RXRG | ENSPANP00000043481 | ENSPANP00000004047 | Nuclear receptor coactivator. | Retinoid X receptor gamma. | 0.973 |
