node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AR | ERG | ENSPANP00000006052 | ENSPANP00000033004 | Androgen receptor. | ETS transcription factor ERG. | 0.499 |
AR | RUNX1 | ENSPANP00000006052 | ENSPANP00000025646 | Androgen receptor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.575 |
AR | RUNX2 | ENSPANP00000006052 | ENSPANP00000022080 | Androgen receptor. | RUNX family transcription factor 2. | 0.620 |
AR | RUNX3 | ENSPANP00000006052 | ENSPANP00000044766 | Androgen receptor. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.569 |
AR | TMPRSS2 | ENSPANP00000006052 | ENSPANP00000012910 | Androgen receptor. | Transmembrane serine protease 2; Belongs to the peptidase S1 family. | 0.805 |
CBFB | ERG | ENSPANP00000013055 | ENSPANP00000033004 | Core-binding factor subunit beta. | ETS transcription factor ERG. | 0.647 |
CBFB | RUNX1 | ENSPANP00000013055 | ENSPANP00000025646 | Core-binding factor subunit beta. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.978 |
CBFB | RUNX2 | ENSPANP00000013055 | ENSPANP00000022080 | Core-binding factor subunit beta. | RUNX family transcription factor 2. | 0.971 |
CBFB | RUNX3 | ENSPANP00000013055 | ENSPANP00000044766 | Core-binding factor subunit beta. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.958 |
CBFB | TAL1 | ENSPANP00000013055 | ENSPANP00000003091 | Core-binding factor subunit beta. | TAL bHLH transcription factor 1, erythroid differentiation factor. | 0.708 |
ERG | AR | ENSPANP00000033004 | ENSPANP00000006052 | ETS transcription factor ERG. | Androgen receptor. | 0.499 |
ERG | CBFB | ENSPANP00000033004 | ENSPANP00000013055 | ETS transcription factor ERG. | Core-binding factor subunit beta. | 0.647 |
ERG | MYB | ENSPANP00000033004 | ENSPANP00000011033 | ETS transcription factor ERG. | MYB proto-oncogene, transcription factor. | 0.544 |
ERG | RUNX1 | ENSPANP00000033004 | ENSPANP00000025646 | ETS transcription factor ERG. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.589 |
ERG | RUNX2 | ENSPANP00000033004 | ENSPANP00000022080 | ETS transcription factor ERG. | RUNX family transcription factor 2. | 0.742 |
ERG | RUNX3 | ENSPANP00000033004 | ENSPANP00000044766 | ETS transcription factor ERG. | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. | 0.504 |
ERG | SETDB1 | ENSPANP00000033004 | ENSPANP00000003982 | ETS transcription factor ERG. | SET domain bifurcated histone lysine methyltransferase 1. | 0.409 |
ERG | SPI1 | ENSPANP00000033004 | ENSPANP00000007556 | ETS transcription factor ERG. | Spi-1 proto-oncogene. | 0.595 |
ERG | TAL1 | ENSPANP00000033004 | ENSPANP00000003091 | ETS transcription factor ERG. | TAL bHLH transcription factor 1, erythroid differentiation factor. | 0.550 |
ERG | TMPRSS2 | ENSPANP00000033004 | ENSPANP00000012910 | ETS transcription factor ERG. | Transmembrane serine protease 2; Belongs to the peptidase S1 family. | 0.500 |