node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CACUL1 | KBTBD11 | ENSPANP00000016487 | ENSPANP00000033615 | CDK2 associated cullin domain 1; Belongs to the cullin family. | Kelch repeat and BTB domain containing 11. | 0.457 |
CACUL1 | NAE1 | ENSPANP00000016487 | ENSPANP00000046809 | CDK2 associated cullin domain 1; Belongs to the cullin family. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.696 |
CUL1 | CUL3 | ENSPANP00000007582 | ENSPANP00000018144 | Cullin 1; Belongs to the cullin family. | Cullin 3; Belongs to the cullin family. | 0.700 |
CUL1 | KBTBD11 | ENSPANP00000007582 | ENSPANP00000033615 | Cullin 1; Belongs to the cullin family. | Kelch repeat and BTB domain containing 11. | 0.457 |
CUL1 | NAE1 | ENSPANP00000007582 | ENSPANP00000046809 | Cullin 1; Belongs to the cullin family. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.819 |
CUL3 | CUL1 | ENSPANP00000018144 | ENSPANP00000007582 | Cullin 3; Belongs to the cullin family. | Cullin 1; Belongs to the cullin family. | 0.700 |
CUL3 | KBTBD11 | ENSPANP00000018144 | ENSPANP00000033615 | Cullin 3; Belongs to the cullin family. | Kelch repeat and BTB domain containing 11. | 0.457 |
CUL3 | NAE1 | ENSPANP00000018144 | ENSPANP00000046809 | Cullin 3; Belongs to the cullin family. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.776 |
INAVA | KBTBD11 | ENSPANP00000047435 | ENSPANP00000033615 | Innate immunity activator. | Kelch repeat and BTB domain containing 11. | 0.436 |
KBTBD11 | CACUL1 | ENSPANP00000033615 | ENSPANP00000016487 | Kelch repeat and BTB domain containing 11. | CDK2 associated cullin domain 1; Belongs to the cullin family. | 0.457 |
KBTBD11 | CUL1 | ENSPANP00000033615 | ENSPANP00000007582 | Kelch repeat and BTB domain containing 11. | Cullin 1; Belongs to the cullin family. | 0.457 |
KBTBD11 | CUL3 | ENSPANP00000033615 | ENSPANP00000018144 | Kelch repeat and BTB domain containing 11. | Cullin 3; Belongs to the cullin family. | 0.457 |
KBTBD11 | INAVA | ENSPANP00000033615 | ENSPANP00000047435 | Kelch repeat and BTB domain containing 11. | Innate immunity activator. | 0.436 |
KBTBD11 | NAE1 | ENSPANP00000033615 | ENSPANP00000046809 | Kelch repeat and BTB domain containing 11. | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | 0.431 |
KBTBD11 | PIDD1 | ENSPANP00000033615 | ENSPANP00000044660 | Kelch repeat and BTB domain containing 11. | P53-induced death domain protein 1. | 0.412 |
NAE1 | CACUL1 | ENSPANP00000046809 | ENSPANP00000016487 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | CDK2 associated cullin domain 1; Belongs to the cullin family. | 0.696 |
NAE1 | CUL1 | ENSPANP00000046809 | ENSPANP00000007582 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Cullin 1; Belongs to the cullin family. | 0.819 |
NAE1 | CUL3 | ENSPANP00000046809 | ENSPANP00000018144 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Cullin 3; Belongs to the cullin family. | 0.776 |
NAE1 | KBTBD11 | ENSPANP00000046809 | ENSPANP00000033615 | NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily. | Kelch repeat and BTB domain containing 11. | 0.431 |
PIDD1 | KBTBD11 | ENSPANP00000044660 | ENSPANP00000033615 | P53-induced death domain protein 1. | Kelch repeat and BTB domain containing 11. | 0.412 |