STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IGF1RTyrosine-protein kinase receptor. (1367 aa)    
Predicted Functional Partners:
IGF2
IlGF domain-containing protein.
    
 0.999
IRS4
Insulin receptor substrate 4.
    
 0.998
IGF1
Insulin like growth factor 1.
    
 0.998
SHC2
Uncharacterized protein.
    
 0.994
LOC103887915
Uncharacterized protein.
   
 0.993
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
    
 0.992
GAB1
GRB2 associated binding protein 1.
    
 0.992
GRB10
Growth factor receptor bound protein 10.
    
 0.990
INSR
Tyrosine-protein kinase receptor.
  
0.987
IRS2
Insulin receptor substrate 2.
    
 0.985
Your Current Organism:
Papio anubis
NCBI taxonomy Id: 9555
Other names: Anubis baboon, Doguera baboon, Kenya baboon, P. anubis, Papio cynocephalus anubis, Papio doguera, Papio hamadryas anubis, Papio hamadryas doguera, baboon, olive baboon
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